Imaging as an Outcome Measure in Gout Studies: Report from the OMERACT Gout Working Group
Por:
Grainger, R, Dalbeth, N, Keen, H, Durcan, L, Edwards, NL, Perez-Ruiz, F, Diaz-Torne, C, Singh, JA, Khanna, D, Simon, LS, Taylor, WJ
Publicada:
1 dic 2015
Resumen:
Objective. The gout working group at the Outcome Measures in Rheumatology (OMERACT) 12 meeting in 2014 aimed to determine which imaging modalities show the most promise for use as measurement instruments for outcomes in studies of people with chronic gout and to identify the key foci for future research about the performance of these imaging techniques with respect to the OMERACT filter 2.0.
Methods. During the gout session, a systematic literature review of the data addressing imaging modalities including plain radiography (XR), conventional computed tomography (CT), dual-energy computed tomography (DECT), magnetic resonance imaging (MRI), and ultrasound (US) and the fulfillment of the OMERACT filter 2.0 was presented.
Results. The working group identified 3 relevant domains for imaging in gout studies: urate deposition (tophus burden), joint inflammation, and structural joint damage.
Conclusion. The working group prioritized gaps in the data and identified a research agenda.
Filiaciones:
Grainger, R:
Univ Otago Wellington, Dept Med, Wellington, New Zealand.
Diaz-Torne, C:
Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Div Rheumatol, E-08193 Barcelona, Spain.
Univ Auckland, Dept Med, Auckland 1, New Zealand.
Mater Misericordiae Univ Hosp, Dublin, Ireland.
Univ Western Australia, Sch Med & Pharmacol, Perth, WA 6009, Australia.
Univ Florida, Dept Med, Gainesville, FL USA.
Hosp Univ Cruces, Div Rheumatol, Vizcaya, Spain.
BioCruces Hlth Res Inst, Vizcaya, Spain.
Birmingham Vet Affairs Med Ctr, Birmingham, AL USA.
Univ Alabama Birmingham, Birmingham, AL USA.
Univ Michigan, Dept Med, Div Rheumatol, Ann Arbor, MI 48109 USA.
SDG LLC, Cambridge, MA USA.
Green Accepted
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