Imported Zika Virus in a European City: How to Prevent Local Transmission?


Por: Millet, JP, Montalvo, T, Bueno-Mari, R, Romero-Tamarit, A, Prats-Uribe, A, Fernandez, L, Camprubi, E, del Bano, L, Peracho, V, Figuerola, J, Sulleiro, E, Martinez, MJ, Cayla, JA

Publicada: 18 jul 2017
Resumen:
Background: On February 1st 2016 the WHO declared the Zika Virus (ZIKV) infection a worldwide public health emergency because of its rapid expansion and severe complications, such as Guillain-Barre Syndrome or microcephaly in newborn. The huge amount of people traveling to endemic areas and the presence of Aedes albopictus in Barcelona increase the risk of autochtonous transmission. The objective of this study was to describe the first ZIKV cases diagnosed in our city and to analyze the surveillance, prevention, and control measures implemented to avoid autochthonous transmission. Methods: An observational cross-sectional population-based study in Barcelona, Spain was performed. An analysis of the socio-demographic, epidemiological, clinical characteristics, and mosquito control activities of the ZIKV cases detected between January 1st and December 2016 was carried out using a specific ZIKV epidemiological survey of the Barcelona Public Health Agency. Results: A total of 118 notifications of possible ZIKV infections were received, and 44 corresponded to confirmed cases in Barcelona residents. Amongst these, the median age was 35 years and 57% were women. All cases were imported, 48% were Spanish-born and 52% foreign-born. Dominican Republic was the most visited country amongst foreign-born patients and Nicaragua amongst Spanish-born. The most frequent symptoms were exanthema, fever, and arthralgia. Among the 24 diagnosed women, 6 (25%) were pregnant. There was one case of microcephaly outside Barcelona city. Entomological inspections were done at the homes of 19 cases (43.2% of the total) and in 34 (77.3%) public spaces. Vector activity was found in one case of the 44 confirmed cases, and 134 surveillance and vector control were carried out associated to imported ZIKV cases. In all cases prevention measures were recommended to avoid mosquito bites on infected cases. Conclusion: Epidemiological and entomological surveillance are essential for the prevention of autochthonous transmission of arbovirosis that may have a great impact on Public Health. The good coordination between epidemiologists, entomologists, microbiologists, and clinicians is a priority in a touristic city with an intense relationship with endemic countries to minimize the risk of local transmission by competent vectors.

Filiaciones:
Millet, JP:
 Agencia Salut Publ Barcelona, Serv Epidemiol, Barcelona, Spain

 CIBER Epidemiol & Salud Publ, Barcelona, Spain

Montalvo, T:
 CIBER Epidemiol & Salud Publ, Barcelona, Spain

 Agencia Salud Publ Barcelona, Serv Vigilancia & Control Plagas Urbanas, Barcelona, Spain

Bueno-Mari, R:
 Dept Invest & Desarrollo I D, Labs Lokim, Valencia, Spain

Romero-Tamarit, A:
 Agencia Salut Publ Barcelona, Serv Epidemiol, Barcelona, Spain

Prats-Uribe, A:
 Agencia Salut Publ Barcelona, Serv Epidemiol, Barcelona, Spain

 Univ Pompeu Fabra, Agencia Salut Publ Barcelona, Parc Salut Mar, Unitat Docent Med Prevent & Salut Publ, Barcelona, Spain

Fernandez, L:
 Agencia Salud Publ Barcelona, Serv Vigilancia & Control Plagas Urbanas, Barcelona, Spain

Camprubi, E:
 Agencia Salut Publ Barcelona, Serv Epidemiol, Barcelona, Spain

del Bano, L:
 Agencia Salut Publ Barcelona, Serv Epidemiol, Barcelona, Spain

Peracho, V:
 Agencia Salud Publ Barcelona, Serv Vigilancia & Control Plagas Urbanas, Barcelona, Spain

Figuerola, J:
 CIBER Epidemiol & Salud Publ, Barcelona, Spain

 CSIC, Estn Biol Donana, Seville, Spain

Sulleiro, E:
 Univ Autonoma Barcelona, PROSICS Barcelona, Hosp Vall dHebron, Microbiol Dept, Barcelona, Spain

Martinez, MJ:
 Univ Barcelona, Dept Microbiol, Hosp Clin Barcelona, Barcelona, Spain

 Univ Barcelona, ISGlobal, Hosp Clin Barcelona, Barcelona Ctr Int Hlth Res CRESIB, Barcelona, Spain

Cayla, JA:
 Agencia Salut Publ Barcelona, Serv Epidemiol, Barcelona, Spain

 CIBER Epidemiol & Salud Publ, Barcelona, Spain
ISSN: 1664302X





Frontiers in Microbiology
Editorial
FRONTIERS MEDIA SA, AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND, Suiza
Tipo de documento: Article
Volumen: 8 Número:
Páginas:
WOS Id: 000406234200002
ID de PubMed: 28769893
imagen Green Published, gold

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