Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Por: Sims, R, van der Lee, SJ, Naj, AC, Bellenguez, C, Badarinarayan, N, Jakobsdottir, J, Kunkle, BW, Boland, A, Raybould, R, Bis, JC, Martin, ER, Grenier-Boley, B, Heilmann-Heimbach, S, Chouraki, V, Kuzma, AB, Sleegers, K, Vronskaya, M, Ruiz, A, Graham, RR, Olaso, R, Hoffmann, P, Grove, ML, Vardarajan, BN, Hiltunen, M, Nothen, MM, White, CC, Hamilton-Nelson, KL, Epelbaum, J, Maier, W, Choi, SH, Beecham, GW, Dulary, C, Herms, S, Smith, AV, Funk, CC, Derbois, C, Forstner, AJ, Ahmad, S, Li, HD, Bacq, D, Harold, D, Satizabal, CL, Valladares, O, Squassina, A, Thomas, R, Brody, JA, Qu, LM, Sanchez-Juan, P, Morgan, T, Wolters, FJ, Zhao, Y, Garcia, FS, Denning, N, Fornage, M, Malamon, J, Naranjo, MCD, Majounie, E, Mosley, TH, Dombroski, B, Wallon, D, Lupton, MK, Dupuis, J, Whitehead, P, Fratiglioni, L, Medway, C, Jian, XQ, Mukherjee, S, Keller, L, Brown, K, Lin, HH, Cantwell, LB, Panza, F, McGuinness, B, Moreno-Grau, S, Burgess, JD, Solfrizzi, V, Proitsi, P, Adams, HH, Allen, M, Seripa, D, Pastor, P, Cupples, LA, Price, ND, Hannequin, D, Frank-Garcia, A, Levy, D, Chakrabarty, P, Caffarra, P, Giegling, I, Beiser, AS, Giedraitis, V, Hampel, H, Garcia, ME, Wang, X, Lannfelt, L, Mecocci, P, Eiriksdottir, G, Crane, PK, Pasquier, F, Boccardi, V, Henandez, I, Barber, RC, Scherer, M, Tarraga, L, Adams, PM, Leber, M, Chen, Y, Albert, MS, Riedel-Heller, S, Emilsson, V, Beekly, D, Braae, A, Schmidt, R, Blacker, D, Masullo, C, Schmidt, H, Doody, RS, Spalletta, G, Longstreth, WT, Fairchild, TJ, Bossu, P, Lopez, OL, Frosch, MP, Sacchinelli, E, Ghetti, B, Yang, Q, Huebinger, RM, Jessen, F, Li, S, Kamboh, MI, Morris, J, Sotolongo-Grau, O, Katz, MJ, Corcoran, C, Dunstan, M, Braddel, A, Thomas, C, Meggy, A, Marshall, R, Gerrish, A, Chapman, J, Aguilar, M, Taylor, S, Hill, M, Fairen, MD, Hodges, A, Vellas, B, Soininen, H, Kloszewska, I, Daniilidou, M, Uphill, J, Patel, Y, Hughes, JT, Lord, J, Turton, J, Hartmann, AM, Cecchetti, R, Fenoglio, C, Serpente, M, Arcaro, M, Caltagirone, C, Orfei, MD, Ciaramella, A, Pichler, S, Mayhaus, M, Gu, W, Lleo, A, Forte, J, Blesa, R, Barber, IS, Brookes, K, Cupidi, C, Maletta, RG, Carrell, D, Sorbi, S, Moebus, S, Urbano, M, Pilotto, A, Kornhuber, J, Bosco, P, Todd, S, Craig, D, Johnston, J, Gill, M, Lawlor, B, Lynch, A, Fox, NC, Hardy, J, Albin, RL, Apostolova, LG, Arnold, SE, Asthana, S, Atwood, CS, Baldwin, CT, Barnes, LL, Barral, S, Beach, TG, Becker, JT, Bigio, EH, Bird, TD, Boeve, BF, Bowen, JD, Boxer, A, Burke, JR, Burns, JM, Buxbaum, JD, Cairns, NJ, Cao, CH, Carlson, CS, Carlsson, CM, Carney, RM, Carrasquillo, MM, Carroll, SL, Diaz, CC, Chui, HC, Clark, DG, Cribbs, DH, Crocco, EA, DeCarli, C, Dick, M, Duara, R, Evans, DA, Faber, KM, Fallon, KB, Fardo, DW, Farlow, MR, Ferris, S, Foroud, TM, Galasko, DR, Gearing, M, Geschwind, DH, Gilbert, JR, Graff-Radford, NR, Green, RC, Growdon, JH, Hamilton, RL, Harrell, LE, Honig, LS, Huentelman, MJ, Hulette, CM, Hyman, BT, Jarvik, GP, Abner, E, Jin, LW, Jun, G, Karydas, A, Kaye, JA, Kim, R, Kowall, NW, Kramer, JH, LaFerla, FM, Lah, JJ, Leverenz, JB, Levey, AI, Li, G, Lieberman, AP, Lunetta, KL, Lyketsos, CG, Marson, DC, Martiniuk, F, Mash, DC, Masliah, E, McCormick, WC, McCurry, SM, McDavid, AN, Mckee, AC, Mesulam, M, Miller, BL, Miller, CA, Miller, JW, Morris, JC, Murrell, JR, Myers, AJ, O'Bryant, S, Pankratz, VS, Parisi, JE, Paulson, HL, Perry, W, Peskind, E, Pierce, A, Poon, WW, Potter, H, Quinn, JF, Raj, A, Raskind, M, Reisberg, B, Reitz, C, Ringman, JM, Roberson, ED, Rogaeva, E, Rosen, HJ, Rosenberg, RN, Sager, MA, Saykin, AJ, Schneider, JA, Schneider, LS, Seeley, WW, Smith, AG, Sonnen, JA, Spina, S, Stern, RA, Swerdlow, RH, Tanzi, RE, Thornton-Wells, TA, Trojanowski, JQ, Troncoso, JC, Van Deerlin, VM, Van Eldik, LJ, Vinters, HV, Vonsattel, JP, Weintraub, S, Welsh-Bohmer, KA, Wilhelmsen, KC, Williamson, J, Woltjer, RL, Wright, CB, Yu, CE, Yu, L, Garzia, F, Golamaully, F, Septier, G, Engelborghs, S, Vandenberghe, R, De Deyn, PP, Fernadez, CM, Benito, YA, Thonberg, H, Forsell, C, Lilius, L, Kinhult-Stahlbom, A, Kilander, L, Brundin, R, Concari, L, Helisalmi, S, Koivisto, AM, Haapasalo, A, Dermecourt, V, Fievet, N, Hanon, O, Dufouil, C, Brice, A, Ritchie, K, Dubois, B, Himali, JJ, Keene, CD, Tschanz, J, Fitzpatrick, AL, Kukull, WA, Norton, M, Aspelund, T, Larson, EB, Munger, R, Rotter, JI, Lipton, RB, Bullido, MJ, Hofman, A, Montine, TJ, Coto, E, Boerwinkle, E, Petersen, RC, Alvarez, V, Rivadeneira, F, Reiman, EM, Gallo, M, O'Donnell, CJ, Reisch, JS, Bruni, AC, Royall, DR, Dichgans, M, Sano, M, Galimberti, D, St George-Hyslop, P, Scarpini, E, Tsuang, DW, Mancuso, M, Bonuccelli, U, Winslow, AR, Daniele, A, Wu, CK, Peters, O, Nacmias, B, Riemenschneider, M, Heun, R, Brayne, C, Rubinsztein, DC, Bras, J, Guerreiro, R, Al-Chalabi, A, Shaw, CE, Collinge, J, Mann, D, Tsolaki, M, Clarimon, J, Sussams, R, Lovestone, S, O'Donovan, MC, Owen, MJ, Behrens, TW, Mead, S, Goate, AM, Uitterlinden, AG, Holmes, C, Cruchaga, C, Ingelsson, M, Bennett, DA, Powell, J, Golde, TE, Graff, C, De Jager, PL, Morgan, K, Ertekin-Taner, N, Combarros, O, Psaty, BM, Passmore, P, Younkin, SG, Berr, C, Gudnason, V, Rujescu, D, Dickson, DW, Dartigues, JF, DeStefano, AL, Ortega-Cubero, S, Hakonarson, H, Campion, D, Boada, M, Kauwe, JK, Farrer, LA, Van Broeckhoven, C, Ikram, MA, Jones, L, Haines, JL, Tzourio, C, Launer, LJ, Escott-Price, V, Mayeux-, R, Deleuze, JF, Amin, N, Holmans, PA, Pericak-Vance, MA, Amouyel, P, van Duijn, CM, Ramirez, A, Wang, LS, Lambert, JC, Seshadri, S, Williams, J, Schellenberg, GD

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Publicada: 1 sep 2017

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Filiaciones:
Sims, R:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

van der Lee, SJ:
 Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands

Naj, AC:
 Univ Penn, Perelman Sch Med, Ctr Clin Epidemiol & Biostat, Dept Biostat & Epidemiol, Philadelphia, PA USA

 Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA

Bellenguez, C:
 Risk Factors & Mol Determinants Aging Related Dis, RID AGE, U1167, INSERM, Lille, France

 Inst Pasteur, Lille, France

 Univ Lille, Excellence Lab LabEx DISTALZ, U1167, Lille, France

Badarinarayan, N:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Jakobsdottir, J:
 Iceland Heart Assoc, Kopavogur, Iceland

Boland, A:
 Ctr Natl Genotypage, Inst Genom, CEA, Evry, France

Raybould, R:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Bis, JC:
 Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA

Grenier-Boley, B:
 Risk Factors & Mol Determinants Aging Related Dis, RID AGE, U1167, INSERM, Lille, France

 Inst Pasteur, Lille, France

 Univ Lille, Excellence Lab LabEx DISTALZ, U1167, Lille, France

Heilmann-Heimbach, S:
 Univ Bonn, Inst Human Genet, Bonn, Germany

 Univ Bonn, Life & Brain Ctr, Dept Gen, Bonn, Germany

Chouraki, V:
 Boston Univ, Sch Med, Boston, MA 02118 USA

 Framingham Heart Dis Epidemiol Study, Framingham, MA USA

Kuzma, AB:
 Univ Penn, Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA

Sleegers, K:
 VIB, Dept Mol Genet, Neurodegenerat Brain Dis Grp, Antwerp, Belgium

 Univ Antwerp, Inst Born Bunge, Antwerp, Belgium

Vronskaya, M:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Ruiz, A:
 Inst Catala Neurociencies Aplicades, Res Ctr, Barcelona, Spain

 Inst Catala Neurociencies Aplicades, Memory Clin Fundacio ACE, Barcelona, Spain

Graham, RR:
 Genentech Inc, Immunol Biomarkers Grp, San Francisco, CA USA

Olaso, R:
 Ctr Natl Genotypage, Inst Genom, CEA, Evry, France

Hoffmann, P:
 Univ Bonn, Inst Human Genet, Bonn, Germany

 Univ Bonn, Life & Brain Ctr, Dept Gen, Bonn, Germany

 Univ Basel, Div Med Genet, Univ Hosp, Basel, Switzerland

 Univ Basel, Dept Biomed, Basel, Switzerland

Grove, ML:
 Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Sch Publ Hlth, Houston, TX USA

Vardarajan, BN:
 Columbia Univ, Dept Neurol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA

 Columbia Univ, Gertrude H Sergievsky Ctr, New York, NY USA

 Columbia Univ, Dept Neurol, New York, NY USA

Hiltunen, M:
 Univ Eastern Finland, Inst Biomed, Kuopio, Finland

 Kuopio Univ Hosp, Dept Neurol, Kuopio, Finland

Nothen, MM:
 Univ Bonn, Inst Human Genet, Bonn, Germany

 Univ Bonn, Life & Brain Ctr, Dept Gen, Bonn, Germany

White, CC:
 Brigham & Womens Hosp, Dept Neurol & Psychiat, Inst Neurosci, Program Translat NeuroPsychiatr Gen, Boston, MA USA

Epelbaum, J:
 Univ Paris 05, INSERM, Ctr Psychiat & Neurosci, UMR 894, Paris, France

Maier, W:
 German Ctr Neurodegenerat Dis DZNE, Bonn, Germany

 Univ Bonn, Dept Psychiat & Psychotherapy, Bonn, Germany

Choi, SH:
 Boston Univ, Sch Med, Boston, MA 02118 USA

 Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA

Dulary, C:
 Ctr Natl Genotypage, Inst Genom, CEA, Evry, France

Herms, S:
 Univ Bonn, Inst Human Genet, Bonn, Germany

 Univ Bonn, Life & Brain Ctr, Dept Gen, Bonn, Germany

 Univ Basel, Div Med Genet, Univ Hosp, Basel, Switzerland

 Univ Basel, Dept Biomed, Basel, Switzerland

Smith, AV:
 Iceland Heart Assoc, Kopavogur, Iceland

 Univ Iceland, Fac Med, Reykjavik, Iceland

Funk, CC:
 Inst Syst Biol, Seattle, WA USA

Derbois, C:
 Ctr Natl Genotypage, Inst Genom, CEA, Evry, France

Forstner, AJ:
 Univ Bonn, Inst Human Genet, Bonn, Germany

 Univ Bonn, Life & Brain Ctr, Dept Gen, Bonn, Germany

Ahmad, S:
 Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands

Li, HD:
 Inst Syst Biol, Seattle, WA USA

Bacq, D:
 Ctr Natl Genotypage, Inst Genom, CEA, Evry, France

Harold, D:
 Dublin City Univ, Sch Biotechnol, Dublin, Ireland

Satizabal, CL:
 Boston Univ, Sch Med, Boston, MA 02118 USA

 Framingham Heart Dis Epidemiol Study, Framingham, MA USA

Valladares, O:
 Univ Penn, Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA

Squassina, A:
 Univ Cagliari, Dept Biomed Sci, Sect Neurosci & Clin Pharmacol, Cagliari, Italy

Thomas, R:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Brody, JA:
 Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA

Qu, LM:
 Univ Penn, Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA

Sanchez-Juan, P:
 Neurol Serv, Santander, Spain

 Univ Cantabria, Marques Valdecilla Univ Hosp, CIBERNED, Santander, Spain

 IFIMAV, Santander, Spain

Morgan, T:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Wolters, FJ:
 Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands

Zhao, Y:
 Univ Penn, Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA

Garcia, FS:
 Hosp Univ Doctor Negrin, Dept Immunol, Las Palmas Gran Canaria, Spain

Denning, N:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Fornage, M:
 Univ Texas Hlth Sci Ctr Houston, Brown Fdn Inst Mol Med, Houston, TX 77030 USA

Malamon, J:
 Univ Penn, Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA

Naranjo, MCD:
 Hosp Univ Doctor Negrin, Dept Immunol, Las Palmas Gran Canaria, Spain

Majounie, E:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Mosley, TH:
 Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA

 Univ Mississippi, Med Ctr, Dept Geriatr, Jackson, MS 39216 USA

 Univ Mississippi, Med Ctr, Dept Gerontol & Neurol, Jackson, MS 39216 USA

Dombroski, B:
 Univ Penn, Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA

Wallon, D:
 Ctr Hos Rouvray, Sotteville Ies Rouen, France

 Normandy Univ, IRIB, Rouen Univ, U1079,INSERM, Rouen, France

Lupton, MK:
 Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England

 QIMR Berghofer Med Res Inst, Genet Epidemiol, Herston, Qld, Australia

Dupuis, J:
 Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA

Fratiglioni, L:
 Karolinska Univ Hosp Huddinge, Dept Geriatr Med, Stockholm, Sweden

 Karolinska Inst, Dept Neurobiol, Care Sci & Soc, Aging Res Ctr, Stockholm, Sweden

 Stockholm Univ, Stockholm, Sweden

Medway, C:
 Univ Nottingham, Queens Med Ctr, Inst Genet, Nottingham, England

Jian, XQ:
 Univ Texas Hlth Sci Ctr Houston, Brown Fdn Inst Mol Med, Houston, TX 77030 USA

Mukherjee, S:
 Univ Washington, Dept Med, Seattle, WA USA

Keller, L:
 Karolinska Inst, Dept Neurobiol, Care Sci & Soc, Aging Res Ctr, Stockholm, Sweden

 Stockholm Univ, Stockholm, Sweden

Brown, K:
 Univ Nottingham, Queens Med Ctr, Inst Genet, Nottingham, England

Lin, HH:
 Boston Univ, Sch Med, Dept Med, Sect Computat Biomed, Boston, MA 02118 USA

Cantwell, LB:
 Univ Penn, Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA

Panza, F:
 Univ Bari Aldo Moro, Dept Basic Med Neurosci & Sense Organs, Neurodegenerat Dis Unit, Bari, Italy

McGuinness, B:
 Queens Univ, Sch Med Dent & Biomed Sci, Ctr Publ Hlth, Belfast, Antrim, North Ireland

Moreno-Grau, S:
 Inst Catala Neurociencies Aplicades, Res Ctr, Barcelona, Spain

 Inst Catala Neurociencies Aplicades, Memory Clin Fundacio ACE, Barcelona, Spain

Burgess, JD:
 Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA

Solfrizzi, V:
 Univ Bari Aldo Moro, Geriatr Med Memory Unit, Bari, Italy

 Univ Bari Aldo Moro, Rare Dis Ctr, Bari, Italy

Proitsi, P:
 Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England

Adams, HH:
 Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands

Allen, M:
 Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA

Seripa, D:
 IRCCS Casa Sollievo Sofferenza, Geriatr Unit, San Giovanni Rotondo, Italy

 IRCCS Casa Sollievo Sofferenza, Dept Med Sci, Gerontol Geriatr Res Lab, San Giovanni Rotondo, Italy

Pastor, P:
 Univ Perugia, Dept Med, Sect Gerontol & Geriatr, Perugia, Italy

Cupples, LA:
 Framingham Heart Dis Epidemiol Study, Framingham, MA USA

 Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA

Price, ND:
 Inst Syst Biol, Seattle, WA USA

Hannequin, D:
 Normandy Univ, IRIB, Rouen Univ, U1079,INSERM, Rouen, France

 Rouen Univ Hosp, Dept Neurol, Rouen, France

Frank-Garcia, A:
 Univ Autonoma Madrid, Univ Hosp La Paz, Dept Neurol, Madrid, Spain

 Inst Invest Sanitaria Hosp La Paz IdiPaz, Madrid, Spain

 Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

Levy, D:
 Boston Univ, Sch Med, Boston, MA 02118 USA

 Framingham Heart Dis Epidemiol Study, Framingham, MA USA

 NHLBI, Bldg 10, Bethesda, MD 20892 USA

Chakrabarty, P:
 Univ Florida, Dept Neurosci, Ctr Translat Res Neurodegenerat Dis, Gainesville, FL 32610 USA

Caffarra, P:
 Univ Parma, Dept Neurosci, Parma, Italy

 AUSL, Ctr Cognit Disorders, Parma, Italy

Giegling, I:
 Martin Luther Univ Halle Wittenberg, Dept Psychiat, Halle, Germany

Beiser, AS:
 Framingham Heart Dis Epidemiol Study, Framingham, MA USA

 Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA

Giedraitis, V:
 Uppsala Univ, Dept Publ Hlth Geriatr, Uppsala, Sweden

Hampel, H:
 AXA Res Fund & UPMC Chair, Paris, France

 Univ Paris 06, Sorbonne Univ, Paris, France

 Hop La Pitie Salpetriere, Inst Memoire & Malad Alzheimer IM2A, Paris, France

 Hop La Pitie Salpetriere, Dept Neurol, Inst Cerveau & Moelle Epiniere ICM, Paris, France

Garcia, ME:
 NIA, Lab Epidemiol & Populat Sci, Bethesda, MD 20892 USA

Wang, X:
 Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA

Lannfelt, L:
 Uppsala Univ, Dept Publ Hlth Geriatr, Uppsala, Sweden

Mecocci, P:
 Univ Perugia, Dept Med, Sect Gerontol & Geriatr, Perugia, Italy

Eiriksdottir, G:
 Iceland Heart Assoc, Kopavogur, Iceland

Crane, PK:
 Univ Washington, Dept Med, Seattle, WA USA

Pasquier, F:
 Ctr Hosp Univ Lille, Epidemiol & Publ Hlth Dept, Lille, France

 CNR Maj, INSERM, UMRS 1171, Lille, France

Boccardi, V:
 Univ Perugia, Dept Med, Sect Gerontol & Geriatr, Perugia, Italy

Henandez, I:
 Inst Catala Neurociencies Aplicades, Res Ctr, Barcelona, Spain

 Inst Catala Neurociencies Aplicades, Memory Clin Fundacio ACE, Barcelona, Spain

Barber, RC:
 Univ North Texas, Hlth Sci Ctr, Dept Pharmacol & Neurosci, Ft Worth, TX USA

Scherer, M:
 Univ Med Ctr Hamburg Eppendorf, Dept Primary Med Care, Hamburg, Germany

Tarraga, L:
 Inst Catala Neurociencies Aplicades, Res Ctr, Barcelona, Spain

 Inst Catala Neurociencies Aplicades, Memory Clin Fundacio ACE, Barcelona, Spain

Adams, PM:
 Univ Texas Southwestern Med Ctr Dallas, Dept Psychiat, Dallas, TX USA

Leber, M:
 Univ Cologne, Dept Psychiat & Psychotherapy, Cologne, Germany

Chen, Y:
 Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA

Albert, MS:
 Johns Hopkins Univ, Dept Neurol, Baltimore, MD 21218 USA

Riedel-Heller, S:
 Univ Leipzig, Inst Social Med Occupat Hlth & Publ Hlth, Leipzig, Germany

Emilsson, V:
 Iceland Heart Assoc, Kopavogur, Iceland

 Univ Iceland, Fac Pharmaceut Sci, Reykjavik, Iceland

Beekly, D:
 Univ Washington, Natl Alzheimers Coordinating Ctr, Seattle, WA 98195 USA

Braae, A:
 Univ Nottingham, Sch Life Sci, Nottingham, England

 Univ Nottingham, Sch Med, Nottingham, England

Schmidt, R:
 Med Univ Graz, Dept Neurol, Clin Div Neurogeriatr, Graz, Austria

Blacker, D:
 Harvard Sch Publ Hlth, Dept Epidemiol, Boston, MA USA

 Harvard Med Sch, Massachusetts Gen Hosp, Dept Psychiat, Boston, MA USA

Masullo, C:
 Univ Cattolica Sacro Cuore, Dept Neurol, Rome, Italy

Schmidt, H:
 Med Univ Graz, Inst Mol Biol & Biochem, Graz, Austria

Doody, RS:
 Baylor Coll Med, Alzheimers Dis & Memory Disorders Ctr, Houston, TX 77030 USA

Spalletta, G:
 IRCCS, Santa Lucia Fdn, Expt Neuropsychiat Lab, Dept Clin & Behav Neurol, Rome, Italy

Longstreth, WT:
 Univ Washington, Dept Neurol, Seattle, WA 98195 USA

 Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA

Fairchild, TJ:
 Univ North Texas, Hlth Sci Ctr, Off Strategy & Measurement, Ft Worth, TX USA

Bossu, P:
 IRCCS, Santa Lucia Fdn, Expt Neuropsychiat Lab, Dept Clin & Behav Neurol, Rome, Italy

Lopez, OL:
 Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA

 Univ Pittsburgh, Dept Neurol, Pittsburgh, PA 15260 USA

Frosch, MP:
 Massachusetts Gen Hosp, CS Kubik Lab Neuropathol, Charlestown, MA USA

Sacchinelli, E:
 IRCCS, Santa Lucia Fdn, Expt Neuropsychiat Lab, Dept Clin & Behav Neurol, Rome, Italy

Ghetti, B:
 Indiana Univ, Dept Pathol & Lab Med, Indianapolis, IN 46204 USA

Yang, Q:
 Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA

Huebinger, RM:
 Univ Texas Southwestern Med Ctr Dallas, Dept Surg, Dallas, TX USA

Jessen, F:
 German Ctr Neurodegenerat Dis DZNE, Bonn, Germany

 Univ Bonn, Dept Psychiat & Psychotherapy, Bonn, Germany

 Univ Cologne, Dept Psychiat & Psychotherapy, Cologne, Germany

Li, S:
 Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA

Kamboh, MI:
 Univ Pittsburgh, Alzheimers Dis Res Ctr, Pittsburgh, PA USA

 Univ Pittsburgh, Dept Human Genet, Pittsburgh, PA USA

Morris, J:
 Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA

 Washington Univ, Sch Med, Hope Ctr Program Prot Aggregat & Neurodegenerat, St Louis, MO USA

 Washington Univ, Dept Pathol & Immunol, St Louis, MO USA

 Washington Univ, Dept Neurol, St Louis, MO USA

Sotolongo-Grau, O:
 Inst Catala Neurociencies Aplicades, Res Ctr, Barcelona, Spain

 Inst Catala Neurociencies Aplicades, Memory Clin Fundacio ACE, Barcelona, Spain

Katz, MJ:
 Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USA

Corcoran, C:
 Utah State Univ, Dept Math & Stat, Logan, UT 84322 USA

Dunstan, M:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Braddel, A:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Thomas, C:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Meggy, A:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Marshall, R:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Gerrish, A:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Chapman, J:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Aguilar, M:
 Fundacio Recerca Biomed & Social Mutua Terrassa, Barcelona, Spain

 Hosp Univ Mutua Terrassa, Dept Neurol, Memory Unit, Barcelona, Spain

Taylor, S:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Hill, M:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Fairen, MD:
 Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

 Fundacio Recerca Biomed & Social Mutua Terrassa, Barcelona, Spain

Hodges, A:
 Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Old Age Psychiat, London, England

Vellas, B:
 Univ Toulouse, INSERM, U558, Toulouse, France

Soininen, H:
 Kuopio Univ Hosp, Dept Neurol, Kuopio, Finland

Kloszewska, I:
 Med Univ Lodz, Elderly & Psychiat Disorders Dept, Lodz, Poland

Daniilidou, M:
 Univ Leicester, Dept Hlth Sci, Psychiat Elderly, Leicester, Leics, England

Uphill, J:
 UCL Inst Neurol, MRC Prion Unit, Dept Neurodegenerat Dis, London, England

Patel, Y:
 Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England

Hughes, JT:
 Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England

Lord, J:
 Univ Nottingham, Queens Med Ctr, Inst Genet, Nottingham, England

Turton, J:
 Univ Nottingham, Queens Med Ctr, Inst Genet, Nottingham, England

Hartmann, AM:
 Martin Luther Univ Halle Wittenberg, Dept Psychiat, Halle, Germany

Cecchetti, R:
 Univ Perugia, Dept Med, Sect Gerontol & Geriatr, Perugia, Italy

Fenoglio, C:
 Univ Milan, IRCCS Osped Policlin, Fdn Ca Granda, Dept Pathophysiol & Transplantat, Milan, Italy

Serpente, M:
 Univ Milan, IRCCS Osped Policlin, Fdn Ca Granda, Dept Pathophysiol & Transplantat, Milan, Italy

Arcaro, M:
 Univ Milan, IRCCS Osped Policlin, Fdn Ca Granda, Dept Pathophysiol & Transplantat, Milan, Italy

Caltagirone, C:
 IRCCS, Santa Lucia Fdn, Expt Neuropsychiat Lab, Dept Clin & Behav Neurol, Rome, Italy

Orfei, MD:
 IRCCS, Santa Lucia Fdn, Expt Neuropsychiat Lab, Dept Clin & Behav Neurol, Rome, Italy

Ciaramella, A:
 IRCCS, Santa Lucia Fdn, Expt Neuropsychiat Lab, Dept Clin & Behav Neurol, Rome, Italy

Pichler, S:
 Univ Hosp, Dept Psychiat & Psychotherapy, Saarland, Germany

Mayhaus, M:
 Univ Hosp, Dept Psychiat & Psychotherapy, Saarland, Germany

Gu, W:
 Univ Hosp, Dept Psychiat & Psychotherapy, Saarland, Germany

Lleo, A:
 Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

 Autonomous Univ Barcelona, Memory Unit, Dept Neurol, Barcelona, Spain

 Autonomous Univ Barcelona, Hosp Santa Creu & St Pau, St Pau Biomed Res Inst, Barcelona, Spain

Forte, J:
 Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

 Autonomous Univ Barcelona, Memory Unit, Dept Neurol, Barcelona, Spain

 Autonomous Univ Barcelona, Hosp Santa Creu & St Pau, St Pau Biomed Res Inst, Barcelona, Spain

Blesa, R:
 Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

 Autonomous Univ Barcelona, Memory Unit, Dept Neurol, Barcelona, Spain

 Autonomous Univ Barcelona, Hosp Santa Creu & St Pau, St Pau Biomed Res Inst, Barcelona, Spain

Barber, IS:
 Univ Nottingham, Sch Life Sci, Nottingham, England

 Univ Nottingham, Sch Med, Nottingham, England

Brookes, K:
 Univ Nottingham, Sch Life Sci, Nottingham, England

 Univ Nottingham, Sch Med, Nottingham, England

Cupidi, C:
 ASP Catanzaro, Reg Neurogenet Ctr CRN, Lamezia Terme, Italy

Maletta, RG:
 ASP Catanzaro, Reg Neurogenet Ctr CRN, Lamezia Terme, Italy

Carrell, D:
 Univ Washington, Sch Med, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA

Sorbi, S:
 Univ Florence, NEUROFARBA, Dept Neurosci Psychol Drug Res & Child Hlth, Florence, Italy

 IRCCS Don Carlo Gnocchi, Florence, Italy

Moebus, S:
 Univ Duisburg Essen, Univ Hosp Essen, Inst Med Informat Biometry & Epidemiol, Essen, Germany

Urbano, M:
 IRCCS Casa Sollievo Sofferenza, Geriatr Unit, San Giovanni Rotondo, Italy

 IRCCS Casa Sollievo Sofferenza, Dept Med Sci, Gerontol Geriatr Res Lab, San Giovanni Rotondo, Italy

Pilotto, A:
 IRCCS Casa Sollievo Sofferenza, Geriatr Unit, San Giovanni Rotondo, Italy

 IRCCS Casa Sollievo Sofferenza, Dept Med Sci, Gerontol Geriatr Res Lab, San Giovanni Rotondo, Italy

Kornhuber, J:
 Univ Erlangen Nurnberg, Dept Psychiat & Psychotherapy, Erlangen, Germany

Bosco, P:
 Assoc Oasi Maria Santissima Srl, IRCCS, Troina, Italy

Todd, S:
 Queens Univ, Sch Med Dent & Biomed Sci, Ctr Publ Hlth, Belfast, Antrim, North Ireland

Craig, D:
 Queens Univ, Sch Med Dent & Biomed Sci, Ctr Publ Hlth, Belfast, Antrim, North Ireland

Johnston, J:
 Queens Univ, Sch Med Dent & Biomed Sci, Ctr Publ Hlth, Belfast, Antrim, North Ireland

Gill, M:
 St James Hosp, Mercers Inst Res Aging, Dublin, Ireland

 Trinity Coll Dublin, Dublin, Ireland

Lawlor, B:
 St James Hosp, Mercers Inst Res Aging, Dublin, Ireland

 Trinity Coll Dublin, Dublin, Ireland

Lynch, A:
 St James Hosp, Mercers Inst Res Aging, Dublin, Ireland

 Trinity Coll Dublin, Dublin, Ireland

Fox, NC:
 UCL, Inst Neurol, Dept Mol Neurosci, London, England

Hardy, J:
 UCL, Inst Neurol, Dept Mol Neurosci, London, England

Albin, RL:
 Univ Michigan, Dept Neurol, Ann Arbor, MI USA

 VAAAHS, GRECC, Ann Arbor, MI USA

 Michigan Alzheimer Dis Ctr, Ann Arbor, MI USA

Apostolova, LG:
 Indiana Univ Sch Med, Indiana Alzheimers Dis Ctr, Indianapolis, IN 46202 USA

 Indiana Univ, Dept Med & Mol Genet, Indianapolis, IN USA

 Indiana Univ, Dept Neurol, Indianapolis, IN USA

 Indiana Univ, Dept Radiol & Imaging Sci, Indianapolis, IN 46204 USA

Arnold, SE:
 Univ Penn, Dept Psychiat, Perelman Sch Med, Philadelphia, PA 19104 USA

Asthana, S:
 Univ Wisconsin, GRECC, Madison, WI USA

 Univ Wisconsin, Dept Med, Madison, WI USA

 Wisconsin Alzheimers Dis Res Ctr, Madison, WI USA

Atwood, CS:
 Univ Wisconsin, GRECC, Madison, WI USA

 Univ Wisconsin, Dept Med, Madison, WI USA

 Wisconsin Alzheimers Dis Res Ctr, Madison, WI USA

Baldwin, CT:
 Boston Univ, Dept Med, Genet Program, Boston, MA USA

Barnes, LL:
 Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA

 Rush Univ, Med Ctr, Dept Behav Sci, Chicago, IL 60612 USA

 Rush Univ, Rush Alzheimers Dis Ctr, Med Ctr, Chicago, IL 60612 USA

Barral, S:
 Columbia Univ, Dept Neurol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA

 Columbia Univ, Gertrude H Sergievsky Ctr, New York, NY USA

 Columbia Univ, Dept Neurol, New York, NY USA

Beach, TG:
 Banner Sun Hlth Res Inst, Civin Lab Neuropathol, Phoenix, AZ USA

Becker, JT:
 Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA USA

 Univ Pittsburgh, Sch Med, Dept Neurol, Pittsburgh, PA 15261 USA

 Univ Pittsburgh, Sch Med, Dept Psychol, Pittsburgh, PA 15261 USA

Bigio, EH:
 Northwestern Univ, Feinberg Sch Med, Dept Pathol, Chicago, IL 60611 USA

 Northwestern Univ, Feinberg Sch Med, Cognit Neurol & Alzheimers Dis Ctr, Chicago, IL 60611 USA

Bird, TD:
 Univ Washington, Dept Neurol, Seattle, WA 98195 USA

 VA Puget Sound Hlth Care Syst GRECC, Seattle, WA USA

Boeve, BF:
 Mayo Clin, Dept Neurol, Rochester, MN USA

Bowen, JD:
 Swedish Med Ctr, Seattle, WA USA

Boxer, A:
 Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA

Burke, JR:
 Duke Univ, Dept Med, Durham, NC USA

Burns, JM:
 Univ Kansas, Med Ctr, Alzheimers Dis Ctr, Kansas City, KS 66103 USA

Buxbaum, JD:
 Mt Sinai Sch Med, Dept Genet & Genom Sci, New York, NY USA

 Mt Sinai Sch Med, Dept Neurosci, New York, NY USA

 Mt Sinai Sch Med, Dept Psychiat, New York, NY USA

Cairns, NJ:
 Washington Univ, Dept Pathol & Immunol, St Louis, MO USA

Cao, CH:
 Univ S Florida, USF Hlth Byrd Alzheimers Inst, Tampa, FL USA

Carlson, CS:
 Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA

Carlsson, CM:
 Univ Wisconsin, Dept Med, Madison, WI USA

 Wisconsin Alzheimers Dis Res Ctr, Madison, WI USA

Carney, RM:
 Univ Miami, Miller Sch Med, Dept Psychiat & Behav Sci, Miami, FL 33136 USA

Carrasquillo, MM:
 Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA

Carroll, SL:
 Med Univ South Carolina, Dept Pathol & Lab Med, Charleston, SC 29425 USA

Diaz, CC:
 Univ Florida, Dept Neurosci, Ctr Translat Res Neurodegenerat Dis, Gainesville, FL 32610 USA

Chui, HC:
 Univ Southern Calif, Dept Neurol, Los Angeles, CA USA

Clark, DG:
 Med Univ South Carolina, Dept Neurol, Charleston, SC 29425 USA

 Ralph H Johnson VA Med Ctr, Dept Neurol, Charleston, SC USA

Cribbs, DH:
 Univ Calif Irvine, Dept Neurol, Irvine, CA 92717 USA

Crocco, EA:
 Univ Miami, Miller Sch Med, Dept Psychiat & Behav Sci, Miami, FL 33136 USA

DeCarli, C:
 Univ Calif Davis, Dept Neurol, Sacramento, CA 95817 USA

Dick, M:
 Univ Calif Irvine, Inst Memory Impairments & Neurol Disorder, Irvine, CA USA

Duara, R:
 Mt Sinai Med Ctr, Wien Ctr Alzheimers Dis & Memory Disorders, Miami Beach, FL 33140 USA

Evans, DA:
 Rush Univ, Med Ctr, Dept Internal Med, Rush Inst Hlth Aging, Chicago, IL 60612 USA

Faber, KM:
 Indiana Univ, Dept Med & Mol Genet, Indianapolis, IN USA

Fallon, KB:
 Univ Alabama Birmingham, Dept Pathol, Birmingham, AL USA

Fardo, DW:
 Univ Kentucky, Sanders Brown Ctr Aging, Dept Biostat, Lexington, KY 40536 USA

Farlow, MR:
 Indiana Univ, Dept Neurol, Indianapolis, IN USA

Ferris, S:
 NYU, Dept Psychiat, 550 1St Ave, New York, NY 10016 USA

Foroud, TM:
 Indiana Univ, Dept Med & Mol Genet, Indianapolis, IN USA

Galasko, DR:
 Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA

Gearing, M:
 Emory Univ, Dept Pathol & Lab Med, Atlanta, GA 30322 USA

 Emory Univ, Emory Alzheimers Dis Ctr, Atlanta, GA 30322 USA

Geschwind, DH:
 Univ Calif Los Angeles, Neurogenet Program, Los Angeles, CA USA

Graff-Radford, NR:
 Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA

 Mayo Clin, Dept Neurol, Jacksonville, FL 32224 USA

Green, RC:
 Brigham & Womens Hosp, Dept Med, Div Genet, 75 Francis St, Boston, MA 02115 USA

 Brigham & Womens Hosp, Partners Ctr Personalized Genet Med, 75 Francis St, Boston, MA 02115 USA

 Harvard Med Sch, Boston, MA USA

Growdon, JH:
 Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, Boston, MA USA

Hamilton, RL:
 Univ Pittsburgh, Dept Pathol Neuropathol, Pittsburgh, PA USA

Harrell, LE:
 Univ Alabama Birmingham, Dept Neurol, Birmingham, AL USA

Honig, LS:
 Columbia Univ, Dept Neurol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA

Huentelman, MJ:
 Translat Genom Res Inst, Neurogenom Div, Phoenix, AZ USA

Hulette, CM:
 Duke Univ, Dept Pathol, Durham, NC 27706 USA

Hyman, BT:
 Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, Boston, MA USA

Jarvik, GP:
 Univ Washington, Dept Genome Sci, Seattle, WA 98195 USA

 Univ Washington, Dept Med Med Genet, Seattle, WA 98195 USA

Abner, E:
 Univ Kentucky, Sanders Brown Ctr Aging, Coll Publ Hlth, Dept Epidemiol, Lexington, KY 40536 USA

Jin, LW:
 Univ Calif Davis, Dept Pathol & Lab Med, Sacramento, CA 95817 USA

Jun, G:
 Boston Univ, Dept Med, Genet Program, Boston, MA USA

 Boston Univ, Dept Biostat, Boston, MA 02215 USA

 Boston Univ, Dept Ophthalmol, Boston, MA USA

Karydas, A:
 Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA

Kaye, JA:
 Oregon Hlth & Sci Univ, Dept Neurol, Portland, OR 97201 USA

 Portland VA Med Ctr, Dept Neurol, Portland, OR USA

Kim, R:
 Univ Calif Irvine, Dept Pathol & Lab Med, Irvine, CA USA

Kowall, NW:
 Boston Univ, Dept Neurol, Boston, MA USA

 Boston Univ, Dept Pathol, Boston, MA USA

Kramer, JH:
 Univ Calif San Francisco, Dept Neuropsychol, San Francisco, CA 94143 USA

LaFerla, FM:
 Univ Calif Irvine, Dept Neurobiol & Behav, Irvine, CA USA

Lah, JJ:
 Emory Univ, Dept Neurol, Atlanta, GA USA

Leverenz, JB:
 Cleveland Clin, Cleveland Clin Lou Ruvo Ctr Brain Hlth, Cleveland, OH 44106 USA

Levey, AI:
 Emory Univ, Dept Neurol, Atlanta, GA USA

Li, G:
 Univ Washington, Sch Med, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA

 VA Puget Sound Hlth Care Syst GRECC, Seattle, WA USA

Lieberman, AP:
 Univ Michigan, Dept Pathol, Ann Arbor, MI 48109 USA

Lunetta, KL:
 Boston Univ, Dept Biostat, Boston, MA 02215 USA

Lyketsos, CG:
 Johns Hopkins Univ, Dept Psychiat, Baltimore, MD USA

Marson, DC:
 Univ Alabama Birmingham, Dept Neurol, Birmingham, AL USA

Martiniuk, F:
 NYU, Dept Med Pulm, New York, NY USA

Mash, DC:
 Univ Miami, Dept Neurol, Miami, FL USA

Masliah, E:
 Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA

 Univ Calif San Diego, Dept Pathol, La Jolla, CA 92093 USA

McCormick, WC:
 Univ Washington, Dept Med, Seattle, WA USA

McCurry, SM:
 Univ Washington, Sch Nursing, Northwest Res Grp Aging, Seattle, WA 98195 USA

McDavid, AN:
 Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA

Mckee, AC:
 Boston Univ, Dept Neurol, Boston, MA USA

 Boston Univ, Dept Pathol, Boston, MA USA

Mesulam, M:
 Northwestern Univ, Feinberg Sch Med, Cognit Neurol & Alzheimers Dis Ctr, Chicago, IL 60611 USA

 Northwestern Univ, Feinberg Sch Med, Dept Neurol, Chicago, IL USA

Miller, BL:
 Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA

Miller, CA:
 Univ Southern Calif, Dept Pathol, Los Angeles, CA 90089 USA

Miller, JW:
 Univ Calif Davis, Dept Pathol & Lab Med, Sacramento, CA 95817 USA

Morris, JC:
 Washington Univ, Dept Pathol & Immunol, St Louis, MO USA

 Washington Univ, Dept Neurol, St Louis, MO USA

Murrell, JR:
 Indiana Univ, Dept Pathol & Lab Med, Indianapolis, IN 46204 USA

 Indiana Univ, Dept Med & Mol Genet, Indianapolis, IN USA

Myers, AJ:
 Univ Miami, Miller Sch Med, Dept Psychiat & Behav Sci, Miami, FL 33136 USA

O'Bryant, S:
 Univ North Texas, Hlth Sci Ctr, Div Geriatr, Internal Med, Ft Worth, TX USA

Pankratz, VS:
 Univ Calif Davis, Dept Neurol, Sacramento, CA 95817 USA

 Univ New Mexico, Hlth Sci Ctr, Dept Internal Med, Albuquerque, NM 87131 USA

Parisi, JE:
 Mayo Clin, Dept Lab Med & Pathol, Rochester, MN USA

Paulson, HL:
 Univ Michigan, Dept Neurol, Ann Arbor, MI USA

 Michigan Alzheimer Dis Ctr, Ann Arbor, MI USA

Peskind, E:
 Univ Washington, Sch Med, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA

Pierce, A:
 Univ Calif Irvine, Dept Neurol, Irvine, CA 92717 USA

Poon, WW:
 Univ Calif Irvine, Inst Memory Impairments & Neurol Disorder, Irvine, CA USA

Potter, H:
 Univ Colorado, Sch Med, Dept Neurol, Aurora, CO USA

Quinn, JF:
 Oregon Hlth & Sci Univ, Dept Neurol, Portland, OR 97201 USA

 Portland VA Med Ctr, Dept Neurol, Portland, OR USA

Raj, A:
 Univ S Florida, USF Hlth Byrd Alzheimers Inst, Tampa, FL USA

Raskind, M:
 Univ Washington, Sch Med, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA

Reisberg, B:
 NYU, Dept Psychiat, 550 1St Ave, New York, NY 10016 USA

 NYU, Alzheimers Dis Ctr, New York, NY USA

Reitz, C:
 Columbia Univ, Gertrude H Sergievsky Ctr, New York, NY USA

 Columbia Univ, Dept Neurol, New York, NY USA

 Columbia Univ, Dept Epidemiol, New York, NY USA

Ringman, JM:
 Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90024 USA

Roberson, ED:
 Univ Alabama Birmingham, Dept Neurol, Birmingham, AL USA

Rogaeva, E:
 Univ Toronto, Tanz Ctr Res Neurodegenerat Dis, Toronto, ON, Canada

Rosen, HJ:
 Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA

Rosenberg, RN:
 Univ Texas Southwestern Med Ctr Dallas, Dept Neurol, Dallas, TX USA

Sager, MA:
 Univ Wisconsin, Dept Med, Madison, WI USA

Saykin, AJ:
 Indiana Univ, Dept Med & Mol Genet, Indianapolis, IN USA

 Indiana Univ, Dept Radiol & Imaging Sci, Indianapolis, IN 46204 USA

Schneider, JA:
 Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA

 Rush Univ, Rush Alzheimers Dis Ctr, Med Ctr, Chicago, IL 60612 USA

 Rush Univ, Med Ctr, Dept Pathol Neuropathol, Chicago, IL 60612 USA

Schneider, LS:
 Univ Southern Calif, Dept Neurol, Los Angeles, CA USA

 Univ Southern Calif, Dept Psychiat, Los Angeles, CA USA

Seeley, WW:
 Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA

Smith, AG:
 Univ S Florida, USF Hlth Byrd Alzheimers Inst, Tampa, FL USA

Sonnen, JA:
 Univ Washington, Dept Pathol, Seattle, WA 98195 USA

Spina, S:
 Indiana Univ, Dept Pathol & Lab Med, Indianapolis, IN 46204 USA

Stern, RA:
 Boston Univ, Dept Neurol, Boston, MA USA

Swerdlow, RH:
 Univ Kansas, Med Ctr, Alzheimers Dis Ctr, Kansas City, KS 66103 USA

Tanzi, RE:
 Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, Boston, MA USA

Thornton-Wells, TA:
 Novartis Inst Biomed Res, Translat Med, Cambridge, MA USA

Trojanowski, JQ:
 Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA

Troncoso, JC:
 Johns Hopkins Univ, Dept Pathol, Baltimore, MD USA

Van Deerlin, VM:
 Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA

Van Eldik, LJ:
 Univ Kentucky, Sanders Brown Ctr Aging, Dept Anat & Neurobiol, Lexington, KY 40536 USA

Vinters, HV:
 Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90024 USA

 Univ Calif Los Angeles, Dept Pathol & Lab Med, Los Angeles, CA USA

Vonsattel, JP:
 Columbia Univ, Dept Pathol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA

Weintraub, S:
 Northwestern Univ, Feinberg Sch Med, Cognit Neurol & Alzheimers Dis Ctr, Chicago, IL 60611 USA

 Northwestern Univ, Dept Psychiat, Feinberg Sch Med, Chicago, IL USA

Welsh-Bohmer, KA:
 Duke Univ, Dept Med, Durham, NC USA

 Duke Univ, Dept Psychiat & Behav Sci, Durham, NC USA

Wilhelmsen, KC:
 Univ North Carolina Chapel Hill, Dept Genet, Chapel Hill, NC USA

Williamson, J:
 Columbia Univ, Dept Neurol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA

Woltjer, RL:
 Emory Univ, Dept Neurol, Atlanta, GA USA

Wright, CB:
 Oregon Hlth & Sci Univ, Dept Pathol, Portland, OR 97201 USA

Yu, CE:
 Univ Miami, Miller Sch Med, Dept Neurol, Evelyn F McKnight Brain Inst, Miami, FL 33136 USA

Yu, L:
 Univ Washington, Dept Med, Seattle, WA USA

Garzia, F:
 Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA

 Rush Univ, Rush Alzheimers Dis Ctr, Med Ctr, Chicago, IL 60612 USA

Golamaully, F:
 Ctr Natl Genotypage, Inst Genom, CEA, Evry, France

Septier, G:
 Ctr Natl Genotypage, Inst Genom, CEA, Evry, France

Engelborghs, S:
 Univ Antwerp, Inst Born Bunge, Antwerp, Belgium

 Hosp Network Antwerp, Dept Neurol, Antwerp, Belgium

 Hosp Network Antwerp, Memory Clin, Antwerp, Belgium

Vandenberghe, R:
 Hosp Network Antwerp, Dept Neurol, Antwerp, Belgium

 Hosp Network Antwerp, Memory Clin, Antwerp, Belgium

 Univ Leuven, Dept Neurol, Lab Cognit Neurol, Leuven, Belgium

De Deyn, PP:
 Univ Antwerp, Inst Born Bunge, Antwerp, Belgium

 Hosp Network Antwerp, Dept Neurol, Antwerp, Belgium

 Hosp Network Antwerp, Memory Clin, Antwerp, Belgium

Fernadez, CM:
 Hosp Univ Doctor Negrin, Dept Immunol, Las Palmas Gran Canaria, Spain

Benito, YA:
 Hosp Univ Doctor Negrin, Dept Immunol, Las Palmas Gran Canaria, Spain

Thonberg, H:
 Karolinska Univ, Hosp Huddinge, Genet Unit, Dept Geriatr Med, Stockholm, Sweden

 Karolinska Inst, KIADRC, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden

Forsell, C:
 Karolinska Univ, Hosp Huddinge, Genet Unit, Dept Geriatr Med, Stockholm, Sweden

 Karolinska Inst, KIADRC, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden

Lilius, L:
 Karolinska Univ, Hosp Huddinge, Genet Unit, Dept Geriatr Med, Stockholm, Sweden

 Karolinska Inst, KIADRC, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden

Kinhult-Stahlbom, A:
 Karolinska Univ, Hosp Huddinge, Genet Unit, Dept Geriatr Med, Stockholm, Sweden

 Karolinska Inst, KIADRC, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden

Kilander, L:
 Uppsala Univ, Dept Publ Hlth Geriatr, Uppsala, Sweden

Brundin, R:
 Uppsala Univ, Dept Publ Hlth Geriatr, Uppsala, Sweden

Concari, L:
 Univ Parma, Dept Neurosci, Parma, Italy

 AUSL, Ctr Cognit Disorders, Parma, Italy

Helisalmi, S:
 Kuopio Univ Hosp, Dept Neurol, Kuopio, Finland

 Univ Eastern Finland, Inst Clin Med Neurol, Kuopio, Finland

Koivisto, AM:
 Kuopio Univ Hosp, Dept Neurol, Kuopio, Finland

 Univ Eastern Finland, Inst Clin Med Neurol, Kuopio, Finland

Haapasalo, A:
 Kuopio Univ Hosp, Dept Neurol, Kuopio, Finland

 Univ Eastern Finland, Inst Clin Med Neurol, Kuopio, Finland

Dermecourt, V:
 CHU Lille, Memory Ctr Lille, Ctr Memoire Ressources & Rech, Lille, France

Fievet, N:
 Risk Factors & Mol Determinants Aging Related Dis, RID AGE, U1167, INSERM, Lille, France

 Inst Pasteur, Lille, France

 Univ Lille, Excellence Lab LabEx DISTALZ, U1167, Lille, France

 Univ Paris 05, Hop Broca, AP HP, Geriatr Dept,EA 4468, Paris, France

Hanon, O:
 Boston Univ, Sch Med, Boston, MA 02118 USA

 Univ Paris 05, Hop Broca, AP HP, Geriatr Dept,EA 4468, Paris, France

Dufouil, C:
 Univ Bordeaux, Neuroepidemiol, Bordeaux, France

 INSERM, UMR 897, Neuroepidemiol, Bordeaux, France

Brice, A:
 Univ Paris 06, UPMC, Sorbonne Univ,CNRS,UMR 7225,UMRS 1127, Inst Cerveau & Moelle Epinisre,INSERM,U1127, Paris, France

 Hop La Pitie Salpetriere, AP HP, Dept Genet, Paris, France

Ritchie, K:
 La Colombiere Hosp, INSERM, U1061, Montpellier, France

Dubois, B:
 Hop La Pitie Salpetriere, AP HP, Dept Neurol, Inst Memoire & Malad Alzheimer IM2A, Paris, France

 Inst Cerveau & Moelle Epiniere ICM, Inst Neurosci Translationnelles Paris IHU A ICM, Paris, France

 Inst Cerveau & Moelle Epiniere ICM, CNRS, UMRS 975, INSERM, Paris, France

 Univ Paris 06, Hop La Pitie Salpetriere, AP HP, Sorbonne Univ, Paris, France

Keene, CD:
 Univ Washington, Dept Pathol, Seattle, WA 98195 USA

Tschanz, J:
 Utah State Univ, Dept Math & Stat, Logan, UT 84322 USA

Fitzpatrick, AL:
 Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA

 Univ Washington, Dept Family Med, Seattle, WA 98195 USA

Kukull, WA:
 Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA

Norton, M:
 Utah State Univ, Dept Math & Stat, Logan, UT 84322 USA

Aspelund, T:
 Iceland Heart Assoc, Kopavogur, Iceland

 Univ Iceland, Ctr Publ Hlth, Reykjavik, Iceland

Larson, EB:
 Univ Washington, Dept Med, Seattle, WA USA

 Grp Hlth, Res Inst, Seattle, WA USA

Munger, R:
 Utah State Univ, Dept Math & Stat, Logan, UT 84322 USA

Rotter, JI:
 Harbor UCLA Med Ctr, Los Angeles BioMed Res Inst, Inst Translat Genom & Populat Sci, Torrance, CA 90509 USA

Lipton, RB:
 Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USA

Bullido, MJ:
 Inst Invest Sanitaria Hosp La Paz IdiPaz, Madrid, Spain

 Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

 UAM, CSIC, Ctr Biol Mol Severo Ochoa, Madrid, Spain

Hofman, A:
 Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands

Montine, TJ:
 Univ Washington, Dept Pathol, Seattle, WA 98195 USA

Coto, E:
 Univ Cent Asturias, Mol Genet Lab Hosp, Oviedo, Spain

Boerwinkle, E:
 Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Sch Publ Hlth, Houston, TX USA

 Baylor Coll Med, Human Genome Sequencing Ctr, Houston, TX 77030 USA

Petersen, RC:
 Mayo Clin, Dept Neurol, Rochester, MN USA

Alvarez, V:
 Univ Cent Asturias, Mol Genet Lab Hosp, Oviedo, Spain

Rivadeneira, F:
 Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands

 Erasmus Univ, Med Ctr, Dept Internal Med, Rotterdam, Netherlands

 Netherlands Consortium Hlth Aging & Natl Genom In, Leiden, Netherlands

Reiman, EM:
 Translat Genom Res Inst, Neurogenom Div, Phoenix, AZ USA

 Arizona Alzheimers Consortium, Phoenix, AZ USA

 Banner Alzheimers Inst, Phoenix, AZ USA

 Univ Arizona, Dept Psychiat, Phoenix, AZ USA

Gallo, M:
 ASP Catanzaro, Reg Neurogenet Ctr CRN, Lamezia Terme, Italy

O'Donnell, CJ:
 Framingham Heart Dis Epidemiol Study, Framingham, MA USA

Reisch, JS:
 Univ Texas Southwestern Med Ctr Dallas, Dept Clin Sci, Dallas, TX 75390 USA

Bruni, AC:
 ASP Catanzaro, Reg Neurogenet Ctr CRN, Lamezia Terme, Italy

Royall, DR:
 Univ Texas Hlth Sci Ctr San Antonio, Dept Psychiat, San Antonio, TX 78229 USA

 Univ Texas Hlth Sci Ctr San Antonio, Dept Med, San Antonio, TX 78229 USA

 Univ Texas Hlth Sci Ctr San Antonio, Dept Family & Community Med, San Antonio, TX 78229 USA

 Univ Texas Hlth Sci Ctr San Antonio, South Texas Vet Hlth Adm, GRECC, San Antonio, TX 78229 USA

Dichgans, M:
 Klinikum Univ Munchen, Inst Stroke & Dementia Res, Munich, Germany

 German Ctr Neurodegenerat Dis DZNE, Munich, Germany

Sano, M:
 Mt Sinai Sch Med, Dept Psychiat, New York, NY USA

Galimberti, D:
 Univ Milan, IRCCS Osped Policlin, Fdn Ca Granda, Dept Pathophysiol & Transplantat, Milan, Italy

St George-Hyslop, P:
 Univ Toronto, Tanz Ctr Res Neurodegenerat Dis, Toronto, ON, Canada

 Univ Cambridge, Cambridge Inst Med Res, Cambridge, England

Scarpini, E:
 Univ Milan, IRCCS Osped Policlin, Fdn Ca Granda, Dept Pathophysiol & Transplantat, Milan, Italy

Tsuang, DW:
 Univ Washington, Sch Med, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA

 Univ Wisconsin, Dept Med, Madison, WI USA

 VA Puget Sound Hlth Care Syst GRECC, Seattle, WA USA

Mancuso, M:
 Univ Pisa, Neurol Inst, Dept Expt & Clin Med, Pisa, Italy

Bonuccelli, U:
 Univ Pisa, Neurol Inst, Dept Expt & Clin Med, Pisa, Italy

Winslow, AR:
 Pfizer Worldwide Res & Dev, PharmaTherapeut Clin Res, Cambridge, MA USA

Daniele, A:
 Univ Cattolica Sacro Cuore, Inst Neurol, Rome, Italy

Wu, CK:
 Texas Tech Univ, Hlth Sci Ctr, Dept Neurol, Lubbock, TX 79430 USA

 Texas Tech Univ, Hlth Sci Ctr, Dept Pharmacol & Neurosci, Lubbock, TX 79430 USA

Peters, O:
 Charite, Dept Psychiat, Berlin, Germany

Nacmias, B:
 Univ Florence, NEUROFARBA, Dept Neurosci Psychol Drug Res & Child Hlth, Florence, Italy

 IRCCS Don Carlo Gnocchi, Florence, Italy

Riemenschneider, M:
 Univ Hosp, Dept Psychiat & Psychotherapy, Saarland, Germany

Heun, R:
 Univ Bonn, Dept Psychiat & Psychotherapy, Bonn, Germany

Brayne, C:
 Univ Cambridge, Inst Publ Hlth, Cambridge, England

Rubinsztein, DC:
 Univ Cambridge, Cambridge Inst Med Res, Cambridge, England

Bras, J:
 UCL, Inst Neurol, Dept Mol Neurosci, London, England

 Univ Aveiro, Inst Biomed iBiMED, Dept Med Sci, Aveiro, Portugal

Guerreiro, R:
 UCL, Inst Neurol, Dept Mol Neurosci, London, England

 Univ Aveiro, Inst Biomed iBiMED, Dept Med Sci, Aveiro, Portugal

Al-Chalabi, A:
 Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England

Shaw, CE:
 Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England

Collinge, J:
 UCL Inst Neurol, MRC Prion Unit, Dept Neurodegenerat Dis, London, England

Mann, D:
 Univ Manchester, Inst Brain Behav & Mental Hlth, Clin & Cognit Neurosci Res Grp, Manchester, Lancs, England

Tsolaki, M:
 Aristotle Univ Thessaloniki, Med Sch, Dept Neurol 3, Thessaloniki, Greece

Clarimon, J:
 Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

 Autonomous Univ Barcelona, Memory Unit, Dept Neurol, Barcelona, Spain

 Autonomous Univ Barcelona, Hosp Santa Creu & St Pau, St Pau Biomed Res Inst, Barcelona, Spain

Sussams, R:
 Univ Southampton, Sch Med, Div Clin Neurosci, Southampton, Hants, England

Lovestone, S:
 Univ Oxford, Dept Psychiat, Oxford, England

O'Donovan, MC:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Owen, MJ:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Behrens, TW:
 Genentech Inc, Immunol Biomarkers Grp, San Francisco, CA USA

Mead, S:
 UCL Inst Neurol, MRC Prion Unit, Dept Neurodegenerat Dis, London, England

Goate, AM:
 Mt Sinai Sch Med, Dept Neurosci, New York, NY USA

Uitterlinden, AG:
 Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands

 UCL Inst Neurol, MRC Prion Unit, Dept Neurodegenerat Dis, London, England

 Univ Milan, IRCCS Osped Policlin, Fdn Ca Granda, Dept Pathophysiol & Transplantat, Milan, Italy

Holmes, C:
 VA Puget Sound Hlth Care Syst GRECC, Seattle, WA USA

Cruchaga, C:
 Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA

 Washington Univ, Sch Med, Hope Ctr Program Prot Aggregat & Neurodegenerat, St Louis, MO USA

Ingelsson, M:
 Uppsala Univ, Dept Publ Hlth Geriatr, Uppsala, Sweden

Bennett, DA:
 Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA

 Rush Univ, Rush Alzheimers Dis Ctr, Med Ctr, Chicago, IL 60612 USA

Powell, J:
 Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England

Golde, TE:
 Univ Florida, Dept Neurosci, Ctr Translat Res Neurodegenerat Dis, Gainesville, FL 32610 USA

 Florida Alzheimers Dis Res Ctr, Gainesville, FL USA

Graff, C:
 Karolinska Univ Hosp Huddinge, Dept Geriatr Med, Stockholm, Sweden

 Karolinska Inst, KIADRC, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden

De Jager, PL:
 Columbia Univ, Dept Neurol, Med Ctr, Ctr Translat & Syst Neuroimmunol, New York, NY USA

Morgan, K:
 Univ Nottingham, Queens Med Ctr, Inst Genet, Nottingham, England

Ertekin-Taner, N:
 Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA

 Mayo Clin, Dept Neurol, Jacksonville, FL 32224 USA

Combarros, O:
 Neurol Serv, Santander, Spain

 Univ Cantabria, Marques Valdecilla Univ Hosp, CIBERNED, Santander, Spain

 IFIMAV, Santander, Spain

Psaty, BM:
 Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA

 Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

 Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA

 Univ Washington, Dept Hlth Serv, Seattle, WA 98195 USA

Passmore, P:
 Queens Univ, Sch Med Dent & Biomed Sci, Ctr Publ Hlth, Belfast, Antrim, North Ireland

Younkin, SG:
 Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA

 Mayo Clin, Dept Neurol, Jacksonville, FL 32224 USA

Berr, C:
 Hop La Pitie Salpetriere, AP HP, Dept Neurol, Inst Memoire & Malad Alzheimer IM2A, Paris, France

 Hosp Gui de Chauliac, Dept Neurol, CMRR Montpellier, Memory Res & Resources Ctr, Montpellier, France

 Montpellier Univ, Dept Neurol, Montpellier, France

Gudnason, V:
 Iceland Heart Assoc, Kopavogur, Iceland

 Univ Iceland, Fac Med, Reykjavik, Iceland

Rujescu, D:
 Martin Luther Univ Halle Wittenberg, Dept Psychiat, Halle, Germany

Dickson, DW:
 Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA

Dartigues, JF:
 CMRR Bordeaux, Memory Res & Resources Ctr, Bordeaux, France

DeStefano, AL:
 Framingham Heart Dis Epidemiol Study, Framingham, MA USA

 Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA

Ortega-Cubero, S:
 Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

 Univ Navarra, Sch Med, Ctr Appl Med Res, Neurogenet Lab,Div Neurosci, Pamplona, Spain

 Complejo Asistencial Univ Palencia, Dept Neurol, Palencia, Spain

Hakonarson, H:
 Childrens Hosp Philadelphia, Ctr Appl Genom, Philadelphia, PA 19104 USA

Campion, D:
 Ctr Hos Rouvray, Sotteville Ies Rouen, France

 Normandy Univ, IRIB, Rouen Univ, U1079,INSERM, Rouen, France

Boada, M:
 Inst Catala Neurociencies Aplicades, Res Ctr, Barcelona, Spain

 Inst Catala Neurociencies Aplicades, Memory Clin Fundacio ACE, Barcelona, Spain

Kauwe, JK:
 Brigham Young Univ, Dept Biol, Provo, UT 84602 USA

 Brigham Young Univ, Dept Neurosci, Provo, UT 84602 USA

Farrer, LA:
 Boston Univ, Sch Med, Boston, MA 02118 USA

 Boston Univ, Dept Med, Genet Program, Boston, MA USA

 Boston Univ, Dept Biostat, Boston, MA 02215 USA

 Boston Univ, Dept Ophthalmol, Boston, MA USA

 Boston Univ, Dept Neurol, Boston, MA USA

Van Broeckhoven, C:
 VIB, Dept Mol Genet, Neurodegenerat Brain Dis Grp, Antwerp, Belgium

 Univ Antwerp, Inst Born Bunge, Antwerp, Belgium

Ikram, MA:
 Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands

 Erasmus MC Univ, Med Ctr, Dept Neurol, Rotterdam, Netherlands

Jones, L:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Haines, JL:
 Case Western Reserve Univ, Dept Epidemiol & Biostat, Cleveland, OH 44106 USA

Tzourio, C:
 Univ Paris 06, UPMC, Sorbonne Univ,CNRS,UMR 7225,UMRS 1127, Inst Cerveau & Moelle Epinisre,INSERM,U1127, Paris, France

 Univ Bordeaux, UMR 897, Neuroepidemiol, Bordeaux, France

Launer, LJ:
 NIA, Lab Epidemiol & Populat Sci, Bethesda, MD 20892 USA

Escott-Price, V:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Mayeux-, R:
 Columbia Univ, Dept Neurol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA

 Columbia Univ, Gertrude H Sergievsky Ctr, New York, NY USA

 Columbia Univ, Dept Neurol, New York, NY USA

Deleuze, JF:
 Ctr Natl Genotypage, Inst Genom, CEA, Evry, France

Amin, N:
 Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands

Holmans, PA:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Amouyel, P:
 Risk Factors & Mol Determinants Aging Related Dis, RID AGE, U1167, INSERM, Lille, France

 Inst Pasteur, Lille, France

 Univ Lille, Excellence Lab LabEx DISTALZ, U1167, Lille, France

 Ctr Hosp Univ Lille, Epidemiol & Publ Hlth Dept, Lille, France

van Duijn, CM:
 Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands

Ramirez, A:
 Univ Bonn, Inst Human Genet, Bonn, Germany

 Univ Bonn, Dept Psychiat & Psychotherapy, Bonn, Germany

 Univ Cologne, Dept Psychiat & Psychotherapy, Cologne, Germany

Wang, LS:
 Univ Penn, Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA

Lambert, JC:
 Risk Factors & Mol Determinants Aging Related Dis, RID AGE, U1167, INSERM, Lille, France

 Inst Pasteur, Lille, France

Seshadri, S:
 Boston Univ, Sch Med, Boston, MA 02118 USA

 Framingham Heart Dis Epidemiol Study, Framingham, MA USA

Williams, J:
 Cardiff Univ, MRC Ctr Neuropsychiat Genet & Gen, Inst Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales

Schellenberg, GD:
 Univ Penn, Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA

Univ Miami, John P Hussman Inst Human Gen, Miami, FL USA.
Univ Miami, Dept Human Genet, Dr John T Macdonald Fdn, Miami, FL USA.