Effect of copayment policies on initial medication non-adherence according to income: a population-based study


Por: Aznar-Lou, I, Pottegard, A, Fernandez, A, Penarrubia-Maria, MT, Serrano-Blanco, A, Sabes-Figuera, R, Gil-Girbau, M, Fajo-Pascual, M, Moreno-Peral, P, Rubio-Valera, M

Publicada: 1 nov 2018
Resumen:
Objective Copayment policies aim to reduce the burden of medication expenditure but may affect adherence and generate inequities in access to healthcare. The objective was to evaluate the impact of two copayment measures on initial medication non-adherence (IMNA) in several medication groups and by income level. Design A population-based study was conducted using real-world evidence. Setting Primary care in Catalonia (Spain) where two separate copayment measures (fixed copayment and coinsurance) were introduced between 2011 and 2013. Participant Every patient with a new prescription issued between 2011 and 2014 (3 million patients and 10 million prescriptions). Outcomes IMNA was estimated throughout dispensing and invoicing information. Changes in IMNA prevalence after the introduction of copayment policies (immediate level change and trend changes) were estimated through segmented logistic regression. The regression models were stratified by economic status and medication groups. Results Before changes to copayment policies, IMNA prevalence remained stable. The introduction of a fixed copayment was followed by a statistically significant increase in IMNA in poor population, low/middle-income pensioners and low-income non-pensioners (OR from 1.047 to 1.370). In high-income populations, there was a large statistically non-significant increase. IMNA decreased in the low-income population after suspension of the fixed copayment and the introduction of a coinsurance policy that granted this population free access to medications (OR=0.676). Penicillins were least affected while analgesics were affected to the greatest extent. IMNA to medications for chronic conditions increased in low/middle-income pensioners. Conclusion Even nominal charge fixed copayment may generate inequities in access to health services. An anticipation effect and expenses associated with IMNA may have generated short-term costs. A reduction in copayment can protect from non-adherence and have positive, long-term effects. Copayment scenarios could have considerable long-term consequences for health and costs due to increased IMNA in medication for chronic physical conditions.

Filiaciones:
Aznar-Lou, I:
 Inst Recerca St Joan de Deu, Res & Dev Unit, Barcelona, Catalonia, Spain

 Ctr Invest Biomed Red Epidemiol & Salud Publ, Barcelona, Catalunya, Spain

Pottegard, A:
 Univ Southern Denmark, Dept Clin Pharmacol, Odense, Denmark

Fernandez, A:
 Ctr Invest Biomed Red Epidemiol & Salud Publ, Barcelona, Catalunya, Spain

 Publ Hlth Agcy Barcelona, Serv Community Hlth, Barcelona, Catalonia, Spain

Penarrubia-Maria, MT:
 Ctr Invest Biomed Red Epidemiol & Salud Publ, Barcelona, Catalunya, Spain

 Inst Catala Salut, Barcelona, Catalunya, Spain

Serrano-Blanco, A:
 Ctr Invest Biomed Red Epidemiol & Salud Publ, Barcelona, Catalunya, Spain

 Res & Dev Unit, Parc Sanitari St Joan Deu, Barcelona, Catalonia, Spain

Sabes-Figuera, R:
 Ctr Invest Biomed Red Epidemiol & Salud Publ, Barcelona, Catalunya, Spain

 Univ Pompeu Fabra, Fac Econ & Business Sci, Barcelona, Catalonia, Spain

Gil-Girbau, M:
 Primary Care Prevent & Hlth Promot Res Network, Barcelona, Catalonia, Spain

Fajo-Pascual, M:
 Univ Zaragoza, Fac Hlth & Sport Sci, Huesca, Spain

Moreno-Peral, P:
 Dist Atenc Primaria Malaga Guadalhorce, Malaga, Spain

 IBIMA, Malaga, Spain

Rubio-Valera, M:
 Inst Recerca St Joan de Deu, Res & Dev Unit, Barcelona, Catalonia, Spain

 Ctr Invest Biomed Red Epidemiol & Salud Publ, Barcelona, Catalunya, Spain

 Univ Barcelona, Sch Pharm, Barcelona, Catalonia, Spain
ISSN: 20445415
Editorial
BMJ PUBLISHING GROUP, BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND, Reino Unido
Tipo de documento: Article
Volumen: 27 Número: 11
Páginas: 878-891
WOS Id: 000450415200004
ID de PubMed: 29545326
imagen Green Submitted

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