Use of PET and PET/CT for Radiation Therapy Planning: IAEA expert report 2006-2007
Por:
MacManus, M, Nestle, U, Rosenzweig, KE, Carrio, I, Messa, C, Belohlavek, O, Danna, M, Inoue, T, Deniaud-Alexandre, E, Schipani, S, Watanabe, N, Dondi, M, Jeremic, B
Publicada:
1 abr 2009
Resumen:
Positron Emission Tomography (PET) is a significant advance in cancer imaging with great potential for optimizing radiation therapy (RT) treatment planning and thereby improving outcomes for patients. The use of PET and PET/CT in RT planning was reviewed by an international panel. The International Atomic Energy Agency (IAEA) organized two synchronized and overlapping consultants' meetings with experts from different regions of the world in Vienna in July 2006. Nine experts and three IAEA staff evaluated the available data on the use of PET in RT planning, and considered practical methods for integrating it into routine practice. For RT planning. F-18 fluorodeoxyglucose (FDG) was the most valuable pharmaceutical. Numerous Studies supported the routine use of FDG-PET for RT tat-get volume determination in non-small cell lung cancer (NSCLC). There was also evidence for utility of PET in head and neck cancers, lymphoma and in esophageal cancers, with promising preliminary data in many other cancers. The best available approach employs integrated PET/CT images, acquired on a dual scanner in the radiotherapy treatment position after administration of tracer according to a standardized protocol, with careful optimization of images within the RT planning system and carefully considered rules for contouring tumor volumes. PET scans that are not recent or were acquired without proper patient positioning should be repeated for RT planning. PET will play an increasing valuable role in RT planning for a wide range of cancers. When requesting PET scans, physicians should be aware of their potential role in RT planning. (C) 2008 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 91 (2009) 85-94
Filiaciones:
MacManus, M:
Peter MacCallum Canc Ctr, Dept Radiat Oncol, Melbourne, Vic 3002, Australia
Univ Melbourne, Melbourne, Vic, Australia
Nestle, U:
Saarland Univ, Med Ctr, Homburg, Germany
Rosenzweig, KE:
Mem Sloan Kettering Canc Ctr, New York, NY USA
Carrio, I:
Autonomous Univ Barcelona, Barcelona, Spain
Messa, C:
Univ Milano Bicocca, Monza, Italy
Belohlavek, O:
Na Homoice Hosp, Prague, Czech Republic
Danna, M:
Ist Sci San Raffaele, Milan, Italy
Inoue, T:
Yokohama City Univ, Yokohama, Kanagawa 232, Japan
Deniaud-Alexandre, E:
Hop Tenon, F-75970 Paris, France
Schipani, S:
Ist Sci San Raffaele, Milan, Italy
IAEA, A-1400 Vienna, Austria
Watanabe, N:
IAEA, A-1400 Vienna, Austria
Dondi, M:
IAEA, A-1400 Vienna, Austria
Jeremic, B:
IAEA, A-1400 Vienna, Austria
Open Access
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