Extended-spectrum beta-lactamase-producing Escherichia coli in Spain belong to a large variety of multilocus sequence typing types, including ST10 complex/A, ST23 complex/A and ST131/B2
Por:
Oteo, J, Diestra, K, Juan, C, Bautista, V, Novais, A, Perez-Vazquez, M, Moya, B, Miro, E, Coque, TM, Oliver, A, Canton, R, Navarro, F, Campos, J
Publicada:
1 ago 2009
Resumen:
In this study, we investigated the population structure of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in Spain and determined possible associations between specific multilocus sequence typing (MLST) types and ESBL types. Ninety-two ESBL-producing E. coli isolates from 11 Spanish hospitals were studied. The predominant ESBLs in this collection were CTX-M-14 (45.7%), SHV-12 (21.7%) and CTX-M-9 (20.6%). Phylogenetic groups and MLST types were studied. Thirty-seven isolates (40.2%) belonged to phylogroup A, 26 (28.3%) to group B1, 13 (14.1%) to group B2 and 16 (17.4%) to group D. Fifty-six sequence types (STs) were identified, but ST131 (eight isolates) and ST167 (five isolates) were the most prevalent. The most common ST complexeswere ST10 (13 isolates; 14.3%) and ST23 (10 isolates; 11%). Escherichia coli ST131 carried six different ESBLs (CTX-M-1, CTX-M-9, CTX-M-10, CTX-M-14, CTX-M-15 and SHV-12), E. coli ST10 complex carried five ESBLs and E. coli ST23 complex carried four ESBLs. A great diversity of MLST types was observed among Spanish ESBL- producing E. coli isolates. (C) 2009 Elsevier B. V. and the International Society of Chemotherapy. All rights reserved.
Filiaciones:
Oteo, J:
Ctr Nacl Microbiol Virol & Inmunol Sanitarias Maja, Inst Salud Carlos III, Serv Bacteriol, Lab Antibiot, Madrid 28220, Spain
Diestra, K:
Hosp Santa Creu & Sant Pau, Microbiol Serv, Barcelona, Spain
Juan, C:
Hosp Son Dureta, Microbiol Serv, Palma de Mallorca, Spain
Bautista, V:
Ctr Nacl Microbiol Virol & Inmunol Sanitarias Maja, Inst Salud Carlos III, Serv Bacteriol, Lab Antibiot, Madrid 28220, Spain
Novais, A:
Hosp Univ Ramon & Cajal, Microbiol Serv, CIBERESP, Madrid, Spain
CSIC, Unidad Resistencia Antibiot & Virulencia Bacteria, Madrid, Spain
Perez-Vazquez, M:
Ctr Nacl Microbiol Virol & Inmunol Sanitarias Maja, Inst Salud Carlos III, Serv Bacteriol, Lab Antibiot, Madrid 28220, Spain
Moya, B:
Hosp Son Dureta, Microbiol Serv, Palma de Mallorca, Spain
Miro, E:
Hosp Santa Creu & Sant Pau, Microbiol Serv, Barcelona, Spain
Coque, TM:
Hosp Univ Ramon & Cajal, Microbiol Serv, CIBERESP, Madrid, Spain
CSIC, Unidad Resistencia Antibiot & Virulencia Bacteria, Madrid, Spain
Oliver, A:
Hosp Son Dureta, Microbiol Serv, Palma de Mallorca, Spain
Canton, R:
Hosp Univ Ramon & Cajal, Microbiol Serv, CIBERESP, Madrid, Spain
CSIC, Unidad Resistencia Antibiot & Virulencia Bacteria, Madrid, Spain
Navarro, F:
Hosp Santa Creu & Sant Pau, Microbiol Serv, Barcelona, Spain
Campos, J:
Ctr Nacl Microbiol Virol & Inmunol Sanitarias Maja, Inst Salud Carlos III, Serv Bacteriol, Lab Antibiot, Madrid 28220, Spain
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