In pursuit of full recovery in major depressive disorder
Por:
Vicent-Gil, M, Serra-Blasco, M, Navarra-Ventura, G, Trujols, J, Balanza-Martinez, V, Portella, MJ, Cardoner, N
Publicada:
1 ago 2023
Ahead of Print:
1 sep 2022
Resumen:
Many individuals with major depression disorder (MDD) who achieve remission of depressive symptoms, do not perceive themselves as fully recovered. This study explores whether clinical remission is related to functional remission and to patient's perception of recovery, as well as, which factors are associated with their functional and subjective remission. 148 patients with MDD in partial clinical remission were included. Demographics and clinical variables were collected through semi-structured interviews. Objective cognition was evaluated through a neuropsychological battery and subjective cognition through a specific questionnaire. The patient's psychosocial functioning and the perception of their remission were also assessed. Apart from descriptive analysis, Pearson correlations and backward stepwise regression models explored the relationship between demographic, clinical, and cognitive factors with patients' functional and self-perceived remission. From the whole sample, 57 patients (38.5%) were considered to achieve full clinical remission, 38 patients (25.7%) showed functional remission, and 55 patients (37.2%) perceived themselves as remitted. Depressive symptoms and objective and subjective executive function were the factors associated with psychosocial functioning. Besides, depressive symptoms, objective and subjective attention, and subjective executive function were the significant explanatory variables for self-perception of remission. The concept of full recovery from an episode of MDD should not only include the clinician's perspective but also the patient's psychosocial functioning along with their self-perceived remission. As residual depressive symptoms and cognition (objective and subjective) are factors with great contribution to a full recovery, clinicians should specifically address them when choosing therapeutic strategies.
Filiaciones:
Vicent-Gil, M:
Univ Autonoma Barcelona UAB, Ctr Invest Biomed Red Salud Mental, Inst Salud Carlos III CIBERSAM ISCIII,Hosp Santa, St Pau Mental Hlth Res Grp,Inst Invest Biomed St, Barcelona, Spain
Serra-Blasco, M:
Hosp Duran I Reynals, Inst Catala Oncol, ICOnnectat E Hlth Program, Avinguda Granvia Hosp 199-203, Barcelona 08908, Spain
Abat Oliba CEU Univ, Dept Psychol, Carrer Bellesguard 30, Barcelona 08022, Spain
Navarra-Ventura, G:
Univ Autonoma Barcelona UAB, Ctr Invest Biomed Red Salud Mental, Inst Salud Carlos III CIBERSAM ISCIII,Hosp Univ P, Mental Hlth Dept,Inst Invest & Innovacio Parc Tau, Sabadell, Spain
Trujols, J:
Univ Autonoma Barcelona UAB, Ctr Invest Biomed Red Salud Mental, Inst Salud Carlos III CIBERSAM ISCIII,Hosp Santa, St Pau Mental Hlth Res Grp,Inst Invest Biomed St, Barcelona, Spain
Balanza-Martinez, V:
Univ Valencia, Ctr Invest Biomed Red Salud Mental CIBERSAM, Dept Med, Teaching Unit Psychiat & Psychol Med, Valencia, Spain
Portella, MJ:
Univ Autonoma Barcelona UAB, Ctr Invest Biomed Red Salud Mental, Inst Salud Carlos III CIBERSAM ISCIII,Hosp Santa, St Pau Mental Hlth Res Grp,Inst Invest Biomed St, Barcelona, Spain
Cardoner, N:
Univ Autonoma Barcelona UAB, Ctr Invest Biomed Red Salud Mental, Inst Salud Carlos III CIBERSAM ISCIII,Hosp Santa, St Pau Mental Hlth Res Grp,Inst Invest Biomed St, Barcelona, Spain
Univ Autonoma Barcelona UAB, Ctr Invest Biomed Red Salud Mental, Inst Salud Carlos III CIBERSAM ISCIII,Hosp Univ P, Mental Hlth Dept,Inst Invest & Innovacio Parc Tau, Sabadell, Spain
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