In-hospital stroke: a multi-centre prospective registry


Por: Vera, R, Lago, A, Fuentes, B, Gallego, J, Tejada, J, Casado, I, Purroy, F, Delgado, P, Simal, P, Marti-Fabregas, J, Vivancos, J, Diaz-Otero, F, Freijo, M, Masjuan, J

Publicada: 1 ene 2011
Resumen:
Background: In-hospital strokes (IHS) are relatively frequent. Avoidable delays in neurological assessment have been demonstrated. We study the clinical characteristics, neurological care and mortality of IHS. Methods: Multi-centre 1-year prospective study of IHS in 13 hospitals. Demographic and clinical characteristics, admission diagnosis, quality of care, thrombolytic therapy and mortality were recorded. Results: We included 273 IHS patients [156 men; 210 ischaemic strokes (IS), 37 transient ischaemic attacks (TIA) and 26 cerebral haemorrhages]. Mean age was 72 +/- 12 years. Cardiac sources of embolism were present in 138 (50.5%), withdrawal of antithrombotic drugs in 77 (28%) and active cancers in 35 (12.8%). Cardioembolic stroke was the most common subtype of IS (50%). Reasons for admission were programmed or urgent surgery in 70 (25%), cardiac diseases in 50 (18%), TIA or stroke in 30 (11%) and other medical illnesses in 71 (26%). Fifty-two per cent of patients were evaluated by a neurologist within 3 h of stroke onset. Thirty-three patients received treatment with tPA (15.7%). Thirty-one patients (14.7%) could not be treated because of a delay in contacting the neurologist. During hospitalization, 50 patients (18.4%) died, 41 of them because of the stroke or its complications. Conclusions: Cardioembolic IS was the most frequent subtype of stroke. Cardiac sources of embolism, active cancers and withdrawal of antithrombotic drugs constituted special risk factors for IHS. A significant proportion of patients were treated with thrombolysis. However, delays in contacting the neurologist excluded a similar proportion of patients from treatment. IHS mortality was high, mostly because of stroke.

Filiaciones:
Lago, A:
 Hosp La Fe, E-46009 Valencia, Spain

Fuentes, B:
 Hosp La Paz, Madrid, Spain

Gallego, J:
 Hosp Navarra, Pamplona, Spain

Tejada, J:
 Hosp Leon, Leon, Spain

Casado, I:
 Hosp San Pedro de Alcantara, Caceres, Spain

Purroy, F:
 Hosp Arnau Vilanova, Lleida, Spain

Delgado, P:
 Hosp Valle De Hebron, Barcelona, Spain

Simal, P:
 Hosp Clin San Carlos, Madrid, Spain

Marti-Fabregas, J:
 Hosp Santa Creu & Sant Pau, Barcelona, Spain

Vivancos, J:
 Hosp La Princesa, Madrid, Spain

Diaz-Otero, F:
 Hosp Gregorio Maranon, Madrid, Spain

Freijo, M:
 Hosp Basurto, Vizcaya, Spain

Masjuan, J:
 Hosp Ramon & Cajal, Unidad Ictus, E-28034 Madrid, Spain
ISSN: 13515101





EUROPEAN JOURNAL OF NEUROLOGY
Editorial
WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, Reino Unido
Tipo de documento: Article
Volumen: 18 Número: 1
Páginas: 170-176
WOS Id: 000285356300025
ID de PubMed: 20550562

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