First evidence of oncologic neuropathic pain prevalence after screening 8615 cancer patients. Results of the On study
Por:
de Paredes, MLG, Gonzalez, FD, del Prado, PM, Ciriquian, JLM, Frances, SE, Dols, MC, Gonzalez, EE, Granados, ALO, Tarruella, MM, Buron, JDC, Hernandez, A, Miranda, EL, Santos, JPC, Carpeno, FJD
Publicada:
1 abr 2011
Resumen:
Background: Thirty percent to ninety percent of cancer patients suffer from pain, including neuropathic pain (NP), which results in great burden for cancer patients. Thus, it was of great interest to determine NP prevalence in cancer patients in Spain, to raise awareness of the condition, and aiming to improve management of cancer NP.
Patients and methods: A 1-month follow-up prospective epidemiological multicenter study was conducted to assess prevalence and management of NP in Spanish oncologic units. The first 10 cancer patients at each unit diagnosed with NP by the validated Douleur Neuropathique 4 questionnaire (DN4) were recruited.
Results: Of 8615 screened patients, 2567 (30%) suffered from pain. From these, 33% had NP according to investigators and 19% according to DN4 test. Three hundred and sixty-six patients (mean age 62.6 years; 61.2% male) were recruited. Pain decrease at 1 month was greater in patients with metastases (P < 0.01) and depended on treatment (P < 0.05), with 'oxycodone' showing 50.4% pain relief.
Conclusions: NP prevalence in cancer pain is 33%. DN4 reports only about half the cancer NP cases diagnosed by clinicians. Pharmaceutical treatment of cancer pain, including NP, has a greater effect in patients with metastases and seems to depend on the specific treatment used.
Filiaciones:
de Paredes, MLG:
Hosp Ramon & Cajal, Dept Oncol, E-28034 Madrid, Spain
Gonzalez, FD:
Hosp Perpetuo Socorro, Dept Oncol, Alicante, Spain
del Prado, PM:
Hosp Basurto, Dept Oncol, Vizcaya, Spain
Ciriquian, JLM:
Hosp Gen Alicante, Dept Oncol, Alicante, Spain
Frances, SE:
Hosp Univ Getafe, Dept Oncol, Madrid, Spain
Dols, MC:
Complejo Hosp Reg Carlos Haya, Dept Oncol, Malaga, Spain
Gonzalez, EE:
Hosp Univ Cent Asturias, Dept Oncol, Asturias, Spain
Granados, ALO:
Complejo Hosp Jaen, Dept Oncol, Jaen, Spain
Tarruella, MM:
Hosp Santa Creu & Sant Pau, Dept Oncol, Barcelona, Spain
Buron, JDC:
Hosp Torrevieja Salud, Dept Oncol, Alicante, Spain
Hernandez, A:
Hosp Plato, Dept Oncol, Barcelona, Spain
Miranda, EL:
Hosp Univ Mostoles, Dept Oncol, Madrid, Spain
Santos, JPC:
Hosp Donostia, Dept Radiooncol, Guipuzcoa, Spain
Carpeno, FJD:
Hosp Univ La Paz, Dept Oncol, Madrid, Spain
Bronze
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