Methods to Summarize Discrete-Choice Experiments in a Systematic Review: A Scoping Review
Por:
Choudhary, D, Thomas, M, Pacheco-Barrios, K, Zhang, Y, Alonso-Coello, P, Schunemann, H, Hazlewood, G
Publicada:
1 nov 2022
Ahead of Print:
1 jul 2022
Resumen:
Background and Objective Systematic reviews of discrete-choice experiments (DCEs) are being increasingly conducted. The objective of this scoping review was to identify and describe the methodologies that have been used to summarize results across DCEs. Methods We searched the electronic databases MEDLINE and EMBASE from inception to March 18, 2021, to identify English-language systematic reviews of patient preferences that included at least two DCEs and extracted data on attribute importance. The methods used to summarize results across DCEs were classified into narrative, semi-quantitative, and quantitative (meta-analytic) approaches and compared. Approaches to characterize the extent of preference heterogeneity were also described. Results From 7362 unique records, we identified 54 eligible reviews from 2010 to Mar 2021, across a broad range of health conditions. Most (83%) used a narrative approach to summarize findings of DCEs, often citing differences in studies as the reason for not formally pooling findings. Semi-quantitative approaches included summarizing the frequency of the most important attributes, the frequency of attribute statistical significance, or tabulated comparisons of attribute importance for each pair of attributes. One review conducted a meta-analysis using the maximum acceptable risk. While reviews often commented on the heterogeneity of patient preferences, few (6%) addressed this systematically across studies. Conclusion While not commonly used, several semi-quantitative and one quantitative approach for synthesizing results of DCEs were identified, which may be useful for generating summary estimates across DCEs when appropriate. Further work is needed to assess the validity and usefulness of these approaches.
Filiaciones:
Choudhary, D:
Univ Calgary, Dept Med, Calgary, AB, Canada
Thomas, M:
Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada
Pacheco-Barrios, K:
Spaulding Rehabil Hosp, Neuromodulat Ctr & Ctr Clin Res Learning, Boston, MA USA
Massachusetts Gen Hosp, Boston, MA USA
Univ San Ignacio Loyola, Vicerrectorado Invest, Unidad Invest Generac & Sintesis Evidencias Sal, Lima, Peru
Zhang, Y:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON, Canada
Alonso-Coello, P:
Inst Invest Biomed IIB Sant Pau, Ctr Cochrane Iberoamer, Barcelona, Spain
Schunemann, H:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON, Canada
Hazlewood, G:
Univ Calgary, Dept Med, Calgary, AB, Canada
Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada
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