Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study


Por: Podlipnik, S, Carrera, C, Boada, A, Richarz, N, Marcoval, J, Ferreres, JR, Bodet, D, Marti, RM, Segura, S, Sabat, M, Dalmau, J, Quintana, M, Azon, A, Curco, N, Formigon, M, Olivella-Garces, MR, Zaballos, P, Sola, J, Galvany, L, Baliu-Pique, C, Alegre, M, Pasquali, P, Malvehy, J, Puig, S

Publicada: 1 nov 2020
Resumen:
The incidence of melanoma has been increasing worldwide during recent decades. The objective of the study was to analyse the trends in incidence for in situ and invasive melanoma in the Spanish region of Catalonia during the period of 2008-2017. We designed a cross-sectional study with an age-period-cohort analysis of melanoma patient data from the Network of Melanoma Centres in Catalonia. Our database covered a population of over seven million and included a total of 8626 patients with incident melanoma. The main outcome measures were crude and age-standardised incidence rates to the European 2013 standard population. Joinpoint regression models were used to evaluate the population trends. We observed an increase in the age-standardised incidence rate (per 100,000 population) of all melanoma subtypes from 11.56 in 2008 to 13.78 in 2017 with an average annual percent change (AAPC) of 3.5%. This incidence increase was seen exclusively in the older population. Moreover, the stratified analysis showed a statistically significant increase in the age-standardised incidence rate for invasive (AAPC 2.1%) and in situ melanoma (AAPC 6.5%). In conclusion, the incidence of melanoma has continued to increase in the elderly population over recent decades, with a rapidly increasing trend of in situ melanomas and the lentigo maligna subtype.

Filiaciones:
Podlipnik, S:
 Univ Barcelona, Hosp Clin Barcelona, E-08036 Barcelona, Spain

 Inst Invest Biomed August Pi Sunyer IDIBAPS, Barcelona 08036, Spain

Carrera, C:
 Univ Barcelona, Hosp Clin Barcelona, E-08036 Barcelona, Spain

 Inst Invest Biomed August Pi Sunyer IDIBAPS, Barcelona 08036, Spain

 ISCIII, Biomed Res Networking Ctr Rare Dis CIBERER, Barcelona 28029, Spain

Boada, A:
 Univ Autonoma Barcelona, Hosp Univ Germans Trias i Pujol, E-08193 Barcelona, Spain

Richarz, N:
 Univ Autonoma Barcelona, Hosp Univ Germans Trias i Pujol, E-08193 Barcelona, Spain

Marcoval, J:
 Hosp Univ Bellvitge, LHosp Llobregat, Barcelona 08907, Spain

Ferreres, JR:
 Hosp Univ Bellvitge, LHosp Llobregat, Barcelona 08907, Spain

Bodet, D:
 Hosp Valle De Hebron, Barcelona 08035, Spain

Marti, RM:
 Hosp Arnau Vilanova, Lleida 25198, Spain

Segura, S:
 Hosp del Mar, IMIM, Barcelona 08003, Spain

Sabat, M:
 Hosp Parc Tauli, Sabadell 08208, Spain

Dalmau, J:
 Hosp Santa Creu & Sant Pau, Barcelona 08041, Spain

Quintana, M:
 Hosp Univ Sagrat Cor, Barcelona 08029, Spain

Azon, A:
 Hosp St Joan Reus, Reus 43204, Spain

Curco, N:
 Hosp Univ Mutua Terrassa, Terrassa 08221, Spain

Formigon, M:
 Consorci Sanitari Terrassa, Terrassa 08224, Spain

Olivella-Garces, MR:
 Hosp St Joan Despi Moises Broggi, Barcelona 08970, Spain

Zaballos, P:
 Hosp St Pau & Santa Tecla, Tarragona 43003, Spain

Sola, J:
 Hosp Gen Granollers, Barcelona 08402, Spain

Galvany, L:
 Hosp Maig, Barcelona 08025, Spain

Baliu-Pique, C:
 Hosp Igualada, Consorci Sanitari Anoia, Igualada 08700, Spain

Alegre, M:
 Hosp Plato, Barcelona 08006, Spain

Pasquali, P:
 ISCIII, Biomed Res Networking Ctr Rare Dis CIBERER, Barcelona 28029, Spain

 Pius Hosp Valls, Valls 43800, Spain

Malvehy, J:
 Univ Barcelona, Hosp Clin Barcelona, E-08036 Barcelona, Spain

 Inst Invest Biomed August Pi Sunyer IDIBAPS, Barcelona 08036, Spain

 ISCIII, Biomed Res Networking Ctr Rare Dis CIBERER, Barcelona 28029, Spain

Puig, S:
 Univ Barcelona, Hosp Clin Barcelona, E-08036 Barcelona, Spain

 Inst Invest Biomed August Pi Sunyer IDIBAPS, Barcelona 08036, Spain
ISSN: 20770383





Journal of Clinical Medicine
Editorial
MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, Suiza
Tipo de documento: Article
Volumen: 9 Número: 11
Páginas:
WOS Id: 000593317100001
ID de PubMed: 33113930
imagen Green Published, Green Submitted, gold

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