Sociodemographic Factors and Clinical Conditions Associated to Hospitalization in Influenza A (H1N1) 2009 Virus Infected Patients in Spain, 2009-2010
Por:
Gonzalez-Candelas, F, Astray, J, Alonso, J, Castro, A, Canton, R, Galan, JC, Garin, O, Saez, M, Soldevila, N, Baricot, M, Castilla, J, Godoy, P, Delgado-Rodriguez, M, Martin, V, Mayoral, JM, Pumarola, T, Quintana, JM, Tamames, S, Dominguez, A, Navarro, G, Bonfill X., López-Contreras J., Pomar V., Puig M.T., CIBERESP Cases Controls Pandemic
Publicada:
7 mar 2012
Resumen:
The emergence and pandemic spread of a new strain of influenza A (H1N1) virus in 2009 resulted in a serious alarm in clinical and public health services all over the world. One distinguishing feature of this new influenza pandemic was the different profile of hospitalized patients compared to those from traditional seasonal influenza infections. Our goal was to analyze sociodemographic and clinical factors associated to hospitalization following infection by influenza A(H1N1) virus. We report the results of a Spanish nationwide study with laboratory confirmed infection by the new pandemic virus in a case-control design based on hospitalized patients. The main risk factors for hospitalization of influenza A (H1N1) 2009 were determined to be obesity (BMI >= 40, with an odds-ratio [OR] 14.27), hematological neoplasia (OR 10.71), chronic heart disease, COPD (OR 5.16) and neurological disease, among the clinical conditions, whereas low education level and some ethnic backgrounds (Gypsies and Amerinds) were the sociodemographic variables found associated to hospitalization. The presence of any clinical condition of moderate risk almost triples the risk of hospitalization (OR 2.88) and high risk conditions raise this value markedly (OR 6.43). The risk of hospitalization increased proportionally when for two (OR 2.08) or for three or more (OR 4.86) risk factors were simultaneously present
Filiaciones:
Gonzalez-Candelas, F:
Univ Valencia, CSISP, Unidad Mixta Genom & Salud, Valencia, Spain
CIBER Epidemiol & Salud Publ, Madrid, Spain
Astray, J:
Comunidad Madrid, Subdirecc Vigilancia, Madrid, Spain
Alonso, J:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Univ Pompeu Fabra, Dept Ciencies Expt & Salut, Barcelona, Spain
Hosp del Mar, Inst Recerca, Inst Municipal Invest Med, Unitat Recerca Serv Sanitaris, Barcelona, Spain
Castro, A:
CIBER Enfermedades Resp, Madrid, Spain
Canton, R:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Hosp Univ Ramon y Cajal, Microbiol Serv, Madrid, Spain
Galan, JC:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Hosp Univ Ramon y Cajal, Microbiol Serv, Madrid, Spain
Garin, O:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Hosp del Mar, Inst Recerca, Inst Municipal Invest Med, Unitat Recerca Serv Sanitaris, Barcelona, Spain
Saez, M:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Univ Girona, Dept Econ, Girona, Spain
Soldevila, N:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Baricot, M:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Castilla, J:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Inst Salud Publ Navarra, Pamplona, Spain
Godoy, P:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Generalitat Catalunya, Dept Salut, Barcelona, Spain
Delgado-Rodriguez, M:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Univ Jaen, Div Med Prevent & Salud Publ, Jaen, Spain
Martin, V:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Univ Leon, Inst Biomed, E-24071 Leon, Spain
Mayoral, JM:
Serv Vigilancia Andalucia, Seville, Spain
Pumarola, T:
REIPI, Madrid, Spain
Quintana, JM:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Fdn Vasca Innovac & Invest Sanitarias, Sondika, Spain
Tamames, S:
Direcc Gen Salud Publ Desarrollo & Innovaci, Valladolid, Spain
Dominguez, A:
CIBER Epidemiol & Salud Publ, Madrid, Spain
Univ Barcelona, Dept Salut Publ, Barcelona, Spain
Navarro, G:
Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Sant Quintí 77-79, 08041 Barcelona, Spain
Bonfill X.:
Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Sant Quintí 77-79, 08041 Barcelona, Spain
López-Contreras J.:
Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Sant Quintí 77-79, 08041 Barcelona, Spain
Pomar V.:
Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Sant Quintí 77-79, 08041 Barcelona, Spain
Puig M.T.:
Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Sant Quintí 77-79, 08041 Barcelona, Spain
Gold, Green Published
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