Edge-to-Edge Percutaneous Repair of Severe Mitral Regurgitation - State-of-the-Art for Mitraclip (R) Implantation -
Por:
Alegria-Barrero, E, Chan, PH, Paulo, M, Duncan, A, Price, S, Moat, N, Di Mario, C, Serra, A, Garcia, E, Franzen, O
Publicada:
1 abr 2012
Resumen:
MitraClip (R) therapy is a percutaneous edge-to-edge plication of the mitral leaflets, mimicking the Alfieri surgical technique. MitraClip (R) implantation is a safe procedure, and survival outcomes in high-surgical-risk patients are superior to historical controls. Despite these results, questions remain concerning long-term efficacy and durability. The MitraClip (R) device has been studied in a safety and feasibility trial in the USA, a randomized pivotal trial against surgical mitral valve repair. Moreover, MitraClip (R) now has over 2 years of CE-mark approval and a rapidly expanding clinical experience in Europe, primarily in patients at high risk for surgery. A dedicated multidisciplinary team is necessary, as well as thoughtful patient selection, familiarity with the technical aspects of the procedure, including transesophageal ultrasound imaging and post-procedure monitoring. Currently available clinical data and procedural steps are herein reviewed. Because the MitraClip (R) procedure is still relatively new, continued investigation is required to further better define the patient populations that will benefit most. (Circ J 2012; 76: 801-808)
Filiaciones:
Alegria-Barrero, E:
Royal Brompton Hosp, Cardiovasc Biomed Res Unit, London SW3 6NP, England
Chan, PH:
Royal Brompton Hosp, Cardiovasc Biomed Res Unit, London SW3 6NP, England
Paulo, M:
Royal Brompton Hosp, Cardiovasc Biomed Res Unit, London SW3 6NP, England
Duncan, A:
Royal Brompton Hosp, Cardiovasc Biomed Res Unit, London SW3 6NP, England
Price, S:
Royal Brompton Hosp, Cardiovasc Biomed Res Unit, London SW3 6NP, England
Moat, N:
Royal Brompton Hosp, Dept Cardiac Surg, London SW3 6NP, England
Di Mario, C:
Royal Brompton Hosp, Cardiovasc Biomed Res Unit, London SW3 6NP, England
Serra, A:
Santa CreuiSt Pau Hosp, Barcelona, Spain
Garcia, E:
Clin San Carlos Hosp, Dept Cardiol, Madrid, Spain
Franzen, O:
Rigshosp, Dept Cardiol, DK-2100 Copenhagen, Denmark
Bronze
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