Reduced Dose Intravesical Bacillus Calmette-Guerin: Why It Might Not Matter
Por:
Kamat, AM, Lobo, N, Lerner, SP, Li, R, Matulay, JT, Palou, J, Witjes, JA, Roupret, M, Smith, AB, Chang, SS, Shore, ND, Steinberg, GD, Dinney, CP, Svatek, RS, Lamm, DL
Publicada:
1 ene 2022
Resumen:
When it comes to the treatment of patients with non-muscle-invasive bladder cancer (NMIBC) with intravesical bacillus Calmette-Guerin (BCG), two questions must be considered: 1) what dose to give, and 2) for how long? The issue of optimal dose and duration has been the subject of several randomized trials and is especially pertinent in the context of a global BCG shortage. Despite this, there appears to be uncertainty as to whether BCG dose or duration may be compromised in the event of shortage. As such, we wish to summarize the available evidence as an aid to the practicing urologist.
Filiaciones:
Kamat, AM:
Univ Texas MD Anderson Canc Ctr, Dept Urol, Houston, TX 77030 USA
Lobo, N:
Univ Texas MD Anderson Canc Ctr, Dept Urol, Houston, TX 77030 USA
Lerner, SP:
Baylor Coll Med, Scott Dept Urol, Houston, TX 77030 USA
Li, R:
H Lee Moffitt Canc Ctr & Res Inst, Dept Genitourinary Oncol, Tampa, FL USA
Matulay, JT:
Levine Canc Inst Atrium Hlth, Dept Urol, Charlotte, NC USA
Palou, J:
Univ Autonoma Barcelona, Dept Urol, Fundacio Puigvert, Barcelona, Spain
Witjes, JA:
Radboud Univ Nijmegen, Dept Urol, Med Ctr, Nijmegen, Netherlands
Roupret, M:
Sorbonne Univ, Pitie Salpetriere Hosp, AP HP, Predict ONCO URO,GRC 5,Urol, Paris, France
Smith, AB:
Univ N Carolina, Lineberger Comprehens Canc Ctr, Dept Urol, Chapel Hill, NC 27515 USA
Chang, SS:
Vanderbilt Univ, Med Ctr, Dept Urol, 221 Kirkland Hall, Nashville, TN 37235 USA
Shore, ND:
Carolina Urol Res Ctr, Dept Urol, Myrtle Beach, SC USA
Steinberg, GD:
NYU Langone Hlth, Dept Urol, New York, NY USA
Dinney, CP:
Univ Texas MD Anderson Canc Ctr, Dept Urol, Houston, TX 77030 USA
Svatek, RS:
Univ Texas Hlth San Antonio, Dept Urol, San Antonio, TX USA
Lamm, DL:
Univ Arizona, Dept Surg, Phoenix, AZ USA
BCG Oncol, Phoenix, AZ USA
Bronze
|