Recomendations on the Management of Controversies in Advanced Castrate-Resistant Prostate Cancer


Por: Cozar, JM, Solsona, E, Morote, J, Minana, B, Maroto, JP, del Alba, AG, Climent, MA, Carles, J, Alcaraz, A, Castellano, D

Publicada: 1 nov 2012
Resumen:
Context: Controversies and uncertainties among integral management of advanced castration resistant prostate cancer continue to exist despite the number of evidence based clinical practice guidelines published with high international consensus. Objective: To develop a document that reviews the management of controversies in advanced castration resistant prostate cancer, with recommendations from the definition, to the management in hormonal maneuvers, first-line treatment and second-line with new treatments as cabazitaxel or abirarerone and the multidisciplinary approach of the pathology with the goal of finding the most efficient, best time to act and safety. Evidence Acquisition: Two meetings of a multidisciplinary group of experts involved in the management of this disease (Oncologist and Urologist) where pooled analysis of original literature and reached consensus document of recommendations on castration resistant prostate cancer, reviewing and attempting to address the current controversies of the disease. Evidence Synthesis: This document is endorsed by the corresponding Scientific Associations and Working Groups involved in the current management of Genitourinary Tumours: the Spanish Association of Urology (AEU) with the Uro-Oncoloy Group (GUO) and the Spanish Oncology of Genitourinary Group (SOGUG). Conclusions: With the adaptation and implementation of this Document of Recommendations for clinical practice are available for the first time, a real road map for quality, efficiency and safety in the management of patients with CRPC. (c) 2012 AEU. Published by Elsevier Espana, S.L. All rights reserved.

Filiaciones:
Cozar, JM:
 Hosp Univ Virgen de las Nieves, Serv Urol, Granada, Spain

Solsona, E:
 IVO, Serv Urol, Valencia, Spain

Morote, J:
 Hosp Univ Vall diHebron, Serv Urol, Barcelona, Spain

Minana, B:
 Hosp Morales Meseguer, Serv Urol, Murcia, Spain

Maroto, JP:
 Hosp Santa Creu & Sant Pau, Serv Oncol, Barcelona, Spain

del Alba, AG:
 Hosp Univ Son Espases, Serv Oncol, Palma De Mallorca, Spain

Climent, MA:
 IVO, Serv Oncol, Valencia, Spain

Carles, J:
 Inst Oncol Vall dHebron, Serv Oncol, Barcelona, Spain

Alcaraz, A:
 Hosp Clin Barcelona, IDIBAPS, Serv Urol, Barcelona, Spain

Castellano, D:
 Hosp Univ 12 Octubre, Serv Oncol, Madrid, Spain
ISSN: 02104806





Actas Urologicas Espanolas
Editorial
ENE EDICIONES SL, REDACCION, ADMINISTRACION & PUBLICIDAD, ORURO 9 - BAJO IZDA, MADRID, 28016, SPAIN, España
Tipo de documento: Article
Volumen: 36 Número: 10
Páginas: 569-577
WOS Id: 000310928600001
ID de PubMed: 22999347

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