18F PET ligands for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
Por:
Martínez G., Flicker L., Vernooij R.W., Fuentes Padilla P., Zamora J., Roqué i Figuls M., Urrútia G., Bonfill Cosp X.
Publicada:
1 ene 2016
Resumen:
This is the protocol for a review and there is no abstract. The objectives are as follows: To determine the diagnostic test accuracy (DTA) of the 18F PET ligands for Aß (18F-Florbetapir, 18F-Florbetaben, and 18F-Flutemetamol) as the index tests for detecting participants with mild cognitive impairment (MCI) at baseline who would clinically progress to Alzheimer's disease dementia (ADD), or other forms of non-ADD, or any form of dementia at follow-up. To investigate the heterogeneity of the DTA in the included studies, we will evaluate the spectrum of people, referral centres, clinical criteria of MCI, 18F PET ligands for Aß (18F-Florbetapir, 18F-Florbetaben, and 18F-Flutemetamol) techniques, reference standards used, duration of follow-up, aspects of study quality, and conflicts of interest. © 2016 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Filiaciones:
Martínez G.:
Iberoamerican Cochrane Centre, Barcelona, C/ Sant Antoni Maria Claret 167, Pavello 18 Planta 0, Barcelona, 08025, Spain
Flicker L.:
University of Western Australia, Western Australian Centre for Health and Ageing - WACHA, Crawley, Perth, WA 6014, Australia
Vernooij R.W.:
Iberoamerican Cochrane Centre, Barcelona, C/ Sant Antoni Maria Claret 167, Pavello 18 Planta 0, Barcelona, 08025, Spain
Fuentes Padilla P.:
Iberoamerican Cochrane Centre, Barcelona, C/ Sant Antoni Maria Claret 167, Pavello 18 Planta 0, Barcelona, 08025, Spain
Zamora J.:
Ramon y Cajal Institute for Health Research (IRYCIS), CIBER Epidemiology and Public Health, Madrid and Queen Mary University of London, Clinical Biostatistics Unit, Madrid, Ctra. Colmenar km 9,100, Madrid, 28034, Spain
Roqué i Figuls M.:
CIBER Epidemiología y Salud Pública (CIBERESP), Iberoamerican Cochrane Centre - Biomedical Research Institute Sant Pau (IIB Sant Pau), Sant Antoni Maria Claret 171, Edifici Casa Convalescencia, Barcelona, Catalunya, 08041, Spain
Urrútia G.:
CIBER Epidemiología y Salud Pública (CIBERESP), Iberoamerican Cochrane Centre - Biomedical Research Institute Sant Pau (IIB Sant Pau), Sant Antoni Maria Claret 171, Edifici Casa Convalescencia, Barcelona, Catalunya, 08041, Spain
Bonfill Cosp X.:
CIBER Epidemiología y Salud Pública (CIBERESP), Spain, Iberoamerican Cochrane Centre - Biomedical Research Institute Sant Pau (IIB Sant Pau), Sant Antoni Maria Claret, 167, Pavilion 18 (D-13), Barcelona, Catalunya, 08025, Spain
Universitat Autònoma de Barcelona, Sant Antoni Maria Claret, 167, Pavilion 18 (D-13), Barcelona, Catalunya, 08025, Spain
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