Impulsivity, emotional dysregulation and executive function deficits could be associated with alcohol and drug abuse in eating disorders
Por:
Lozano-Madrid M., Bryan D.C., Granero R., Sánchez I., Riesco N., Mallorquí-Bagué N., Jiménez-Murcia S., Treasure J., Fernández-Aranda F.
Publicada:
1 ene 2020
Resumen:
Background: Empirical data suggests a high comorbid occurrence of eating disorders (EDs) and substance use disorders (SUDs), as well as neurological and psychological shared characteristics. However, no prior study has identified the neuropsychological features of this subgroup. This study examines the prevalence of alcohol and/or drug abuse (A/DA) symptoms in ED patients. It also compares the clinical features and neuropsychological performance of ED patients with and without A/DA symptoms. Methods: 145 participants (74.5% females) with various forms of diagnosed EDs underwent a comprehensive clinical (TCI-R, SCL-90-R and EDI-2) and neuropsychological assessment (Stroop, WCST and IGT). Results: Approximately 19% of ED patients (across ED subtypes) had A/DA symptoms. Those with A/DA symptoms showed more impulsive behaviours and higher levels of interoceptive awareness (EDI-2), somatisation (SCL-90-R) and novelty seeking (TCI-R). This group also had a lower score in the Stroop-words measure, made more perseverative errors in the WCST and showed a weaker learning trajectory in the IGT. Conclusions: ED patients with A/DA symptoms display a specific phenotype characterised by greater impulsive personality, emotional dysregulation and problems with executive control. Patients with these temperamental traits may be at high risk of developing a SUD. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
Filiaciones:
Lozano-Madrid M.:
Department of Psychiatry, Bellvitge University Hospital-IDIBELL, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Psychiatry and Mental Health Group, Neuroscience Program, Institut d’Investigació Biomèdica de Bellvitge—IDIBELL, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Ciber Fisiopatologia Obesidad y Nutrición (CIBERobn), Instituto Salud Carlos III, Madrid, 28029, Spain
Bryan D.C.:
Department of Psychological Medicine, Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, SE5 8AF, United Kingdom
Granero R.:
Ciber Fisiopatologia Obesidad y Nutrición (CIBERobn), Instituto Salud Carlos III, Madrid, 28029, Spain
Departament de Psicobiologia i Metodologia, Universitat Autònoma de Barcelona, Barcelona, 08035, Spain
Sánchez I.:
Department of Psychiatry, Bellvitge University Hospital-IDIBELL, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Psychiatry and Mental Health Group, Neuroscience Program, Institut d’Investigació Biomèdica de Bellvitge—IDIBELL, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Ciber Fisiopatologia Obesidad y Nutrición (CIBERobn), Instituto Salud Carlos III, Madrid, 28029, Spain
Riesco N.:
Department of Psychiatry, Bellvitge University Hospital-IDIBELL, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Psychiatry and Mental Health Group, Neuroscience Program, Institut d’Investigació Biomèdica de Bellvitge—IDIBELL, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Ciber Fisiopatologia Obesidad y Nutrición (CIBERobn), Instituto Salud Carlos III, Madrid, 28029, Spain
Mallorquí-Bagué N.:
Ciber Fisiopatologia Obesidad y Nutrición (CIBERobn), Instituto Salud Carlos III, Madrid, 28029, Spain
Department of Psychiatry, Addictive Behavior Unit, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Barcelona, 08001, Spain
Jiménez-Murcia S.:
Department of Psychiatry, Bellvitge University Hospital-IDIBELL, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Psychiatry and Mental Health Group, Neuroscience Program, Institut d’Investigació Biomèdica de Bellvitge—IDIBELL, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Ciber Fisiopatologia Obesidad y Nutrición (CIBERobn), Instituto Salud Carlos III, Madrid, 28029, Spain
Department of Clinical Sciences, School of Medicine and Health Sciences, University of Barcelona, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Treasure J.:
Department of Psychological Medicine, Section of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, SE5 8AF, United Kingdom
Fernández-Aranda F.:
Department of Psychiatry, Bellvitge University Hospital-IDIBELL, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Psychiatry and Mental Health Group, Neuroscience Program, Institut d’Investigació Biomèdica de Bellvitge—IDIBELL, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Ciber Fisiopatologia Obesidad y Nutrición (CIBERobn), Instituto Salud Carlos III, Madrid, 28029, Spain
Department of Clinical Sciences, School of Medicine and Health Sciences, University of Barcelona, L’Hospitalet de Llobregat, Barcelona 08907, Spain
Green Published, gold, All Open Access, Gold, Green
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