A care bundle approach for prevention of ventilator-associated pneumonia


Por: Rello, J, Afonso, E, Lisboa, T, Ricart, M, Balsera, B, Rovira, A, Valles, J, Diaz, E

Publicada: 1 abr 2013
Resumen:
Implementation of care bundles for prevention of ventilator-associated pneumonia (VAP) and its impact on patient outcomes requires validation with long-term follow-up. A collaborative multi-centre cohort study was conducted in five Spanish adult intensive-care units. A care bundle approach based on five measures was implemented after a 3-month baseline period, and compliance, VAP rates, intensive-care unit length of stay (ICU LOS) and duration of mechanical ventilation were prospectively recorded for 16months. There were 149 patients in the baseline period and 885 after the intervention. Compliance with all measures after intervention was <30% (264/885). In spite of this, VAP incidence decreased from 15.5% (23/149) to 11.7% (104/885), after the intervention (p <0.05). This reduction was significantly associated with hand hygiene (OR=0.35), intra-cuff pressure control (OR=0.21), oral hygiene (OR=0.23) and sedation control (OR=0.51). Use of the care bundle was associated with an incidence risk ratio of VAP of 0.78 (95% CI 0.150.99). We documented a reduction of median ICU LOS (from 10 to 6days) and duration of mechanical ventilation (from 8 to 4days) for patients with full bundle compliance (intervention period). Efforts on VAP prevention and outcome improvement should focus on achieving higher compliance in hand and oral hygiene, sedation protocols and intracuff pressure control.

Filiaciones:
Rello, J:
 Univ Autonoma Barcelona, Hosp Vall dHebron, CIBERES, VHIR, E-08193 Barcelona, Spain

Afonso, E:
 Hosp Valle De Hebron, CIBERES, VHIR, Barcelona 08035, Spain

Lisboa, T:
 Hosp Clin, Porto Alegre, RS, Brazil

Ricart, M:
 Hosp Santa Creu & Sant Pau, Barcelona, Spain

Balsera, B:
 Hosp Arnau Vilanova, Lleida, Spain

Rovira, A:
 Hosp Creu Roja, Lhospitalet De Llobregat, Spain

Valles, J:
 Hosp Parc Tauli, CIBERES, Barcelona, Spain

Diaz, E:
 Hosp St Joan Despi, Ciberes, IISPV, Barcelona, Spain
ISSN: 1198743X





CLINICAL MICROBIOLOGY AND INFECTION
Editorial
ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, Reino Unido
Tipo de documento: Article
Volumen: 19 Número: 4
Páginas: 363-369
WOS Id: 000316810200016
ID de PubMed: 22439889
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