Parkinson's Disease: From Genetics to Clinical Practice
Por:
Clarimon, J, Kulisevsky, J
Publicada:
1 dic 2013
Resumen:
Breakthroughs in genetics over the last decade have radically advanced our understanding of the etiological basis of Parkinson's disease (PD). Although much research remains to be done, the main genetic causes of this neurodegenerative disorder are now partially unraveled, allowing us to feel more confident that our knowledge about the genetic architecture of PD will continue to increase exponentially. How and when these discoveries will be introduced into general clinical practice, however, remains uncertain. In this review, we provide a general summary of the progress in the genetics of PD and discuss how this knowledge will contribute to the diagnosis and clinical management of patients with, or at risk of this disorder.
Filiaciones:
Clarimon, J:
Univ Autonoma Barcelona, Hosp St Pau, Inst Invest Biomed St Pau, Dept Neurol, E-08193 Barcelona, Spain.
Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain.
Kulisevsky, J:
Univ Autonoma Barcelona, Hosp St Pau, Inst Invest Biomed St Pau, Dept Neurol, E-08193 Barcelona, Spain.
Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain.
Green Published, All Open Access; Green
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